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Article
Validation and effect of the NASA-TLX score on the assessment of the workload of pediatric robotic operations
The objective of the study was to assess the validity of the NASA-TLX score in rating the workload of pediatric robotic operations.
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Article
Robotic-assisted Kasai portoenterostomy for biliary atresia
Robotic-assisted Kasai portoenterostomy (RAKPE) has been utilized to treat biliary atresia (BA). However, RAKPE is not widely performed and its efficacy remains unknown. We summarized the experience of RAKPE f...
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Article
Comparison of efficacy and safety of robotic surgery and laparoscopic surgery for choledochal cyst in children: a systematic review and proportional meta-analysis
Most commonly, cyst excision and Roux-en-Y hepaticojejunostomy reconstruction are the optimal treatment for choledochal cysts (CC). Robotic surgery (RS) is being conducted with increasing frequency to treat CC...
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Article
Robot-assisted anorectal pull-through for anorectal malformations with rectourethral and rectovesical fistula: feasibility and short-term outcome
Multiple structures in the anorectal area are closely related to defecation, voiding and sexual function. Although laparoscopic-assisted anorectal pull-through is widely accepted as a minimally invasive surgic...
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Article
Open AccessMaternal regulation of biliary disease in neonates via gut microbial metabolites
Maternal seeding of the microbiome in neonates promotes a long-lasting biological footprint, but how it impacts disease susceptibility in early life remains unknown. We hypothesized that feeding butyrate to pr...
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Article
Outcomes in robotic versus laparoscopic-assisted choledochal cyst excision and hepaticojejunostomy in children
Robotic-assisted surgery (RAS) is becoming more popular because of the excellent performance in anastomosis and knot tying, especially in complex surgical procedures such as hepaticojejunostomy. As for operati...
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Article
Open AccessFeasible techniques in robotic thoracoscopic repair of congenital esophageal atresia: case report and literature review
Robotic repair for esophageal atresia (EA) using da Vinci system is challenging. Specific surgical techniques need to be explored to overcome the current hurdles.
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Article
Open AccessLaparoscopic-assisted cyst excision and ductoplasty plus widened portoenterostomy for choledochal cysts with a narrow portal bile duct
Complete cyst excision with Roux-en-Y hepaticojejunostomy is the standard procedure for choledochal cysts (CCs). In recent years, neonates have been increasingly diagnosed with CCs prenatally. Earlier treatmen...
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Article
Open AccessEffects of NRG1 Polymorphisms on Hirschsprung’s Disease Susceptibility: A Meta-analysis
Substantial resources have been devoted to evaluate the relationship between NRG1 variants rs7835688 and rs16879552 and Hirschsprung’s Disease (HSCR) but no consistency exists. This meta-analysis aimed to asse...
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Article
Open AccessEffects of RET, NRG1 and NRG3 Polymorphisms in a Chinese Population with Hirschsprung Disease
The RET proto-oncogene was identified as a major locus involved in Hirschsprung disease (HSCR). A genome-wide association study (GWAS) and whole exome sequencing identified NRG1 and NRG3 as additional HSCR suscep...
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Article
Elevated Th17 cells accompanied by decreased regulatory T cells and cytokine environment in infants with biliary atresia
The aim of this study was to investigate the role of Th17 and Treg cells in biliary atresia (BA) and to assess the liver cytokine environment in BA patients.
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Article
Transanal endorectal pull-through for Hirschsprung’s disease using long cuff dissection and short V-shaped partially resected cuff anastomosis: early and late outcomes
Transanal endorectal pull-through was described by De la Torre-Mondragon’s technique. In the original transanal pull-through procedure, a long rectal muscular cuff was dissected and left for anocolic anastomos...
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Article
Laparoscopic choledochal cyst excision, hepaticojejunostomy, and extracorporeal Roux-en-Y anastomosis: a technical skill and intermediate-term report in 62 cases
This study aimed to present the authors’ technique and the intermediate-term outcome for laparoscopic choledochal cyst excision with Roux-en-Y hepatoenterostomy.
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Article
Laparoscopic extensive colectomy with transanal Soave pull-through for intestinal neuronal dysplasia in 17 children
Open colectomy has been preferred for intestinal neuronal dysplasia type B (IND) due to its low morbidity rate and good functional results. The aim of this study was to investigate the feasibility and results ...
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Article
Nuss operation for pectus excavatum: a single-institution experience
The Nuss procedure for repair of pectus excavatum (PE) has been accepted worldwide because of minimal invasiveness and excellent cosmetic results. We summarized our experience with the treatment of 115 patient...
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Article
Expression and clinical significance of heparanase in neuroblastoma
Previous studies indicate that heparanase (HPA), an endoglycosidase involved in tumor angiogenesis and metastasis, is up-regulated in a variety of malignancies. However, the expression of HPA in neuroblastoma ...
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Article
Duodenal heterotopic pancreas in a child
Heterotopic pancreas is characterized by pancreatic tissue outside the pancreatic bed. However, duodenal heterotopic pancreas in children is rarely reported so far. We describe herein duodenal heterotopic panc...
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Article
Natural jasmonates of different structures suppress the growth of human neuroblastoma cell line SH-SY5Y and its mechanisms
Recent evidence has indicated that members of natural jasmonates, a family of plant stress hormones, exhibit anticancer activity. The current study was undertaken to investigate the effects of jasmonates on the i...
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Article
Expression of matrix metalloproteinase 1 and 2 in congenital choledochal cyst and its clinical significance
The pathogenesis of congenital choledochal cyst (CCC) is still not well elucidated. This study was conducted to detect the expression of matrix metalloproteinase-1 and 2 (MMP-1 and MMP-2) in CCC. The roles of ...
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Article
Expression and clinical significance of stem cell marker CD133 in human neuroblastoma
Recent evidences indicate that CD133, a kind of transmembrane protein, can be used as a marker to isolate stem cells from tumors originating from neural crest. This study was undertaken to explore the expressi...