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Article
Open AccessEmergence of spatio-temporal variations in chemotherapeutic drug efficacy: in-vitro and in-Silico 3D tumour spheroid studies
The mechanisms of action and efficacy of cisplatin and paclitaxel at cell population level are well studied and documented, however the localized spatio-temporal effects of the drugs are less well understood. ...
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Article
Open AccessTemperature affects the silicate morphology in a diatom
Silica deposition by diatoms, a common component of the phytoplankton, has attracted considerable interest given the importance in ecology and materials science. There has recently been a great deal of researc...
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Article
Inference of the Russian drug community from one of the largest social networks in the Russian Federation
The criminal nature of narcotics complicates the direct assessment of a drug community, while having a good understanding of the type of people drawn or currently using drugs is vital for finding effective int...
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Chapter and Conference Paper
Simulation of City Evacuation Coupled to Flood Dynamics
Crowd modeling is one of the key components of risk analysis and evacuation planning in emergency situations. This paper presents a simulation environment for experimenting with different city evacuation scena...
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Article
Open AccessIncreasing risk behaviour can outweigh the benefits of antiretroviral drug treatment on the HIV incidence among men-having-sex-with-men in Amsterdam
The transmission through contacts among MSM (men who have sex with men) is one of the dominating contributors to HIV prevalence in industrialized countries. In Amsterdam, the capital of the Netherlands, the MS...
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Chapter
Laser Dynamics Modelling and Simulation: An Application of Dynamic Load Balancing of Parallel Cellular Automata
This chapter reviews the application of a biologically inspired heuristic technique - Cellular Automata (CA) - for develo** high performance simulations of a well known complex system: the laser.
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Article
Context analysis to support development of virtual reality applications
To develop a usable Virtual Reality system, the prospective context of use of such a system may need to be considered in order to make sure it meets the requirements and restrictions of that context. In this p...
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Chapter and Conference Paper
A Client-Server Engine for Parallel Computation of High-Resolution Planes
The paper describes a visualization mechanism that permits fast extraction of high-resolution slices of interest from large biomedical datasets stored remotely. To provide the user with real-time interaction, ...
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Chapter and Conference Paper
Virtual Reality and Desktop as a Combined Interaction-Visualisation Medium for a Problem-Solving Environment
The paper addresses the problem of how to make a human-machine interaction user-friendlier within a problem-solving environment. Two different projection modalities — virtual reality and desktop solution — are...
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Chapter and Conference Paper
Lattice Boltzmann, a Robust and Accurate Solver for Interactive Computational Hemodynamics
Surgical planning as a treatment for vascular diseases requires fast blood flow simulations that are efficient in handling changing geometry. It is, for example, necessary to try different paths of a planned b...
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Chapter and Conference Paper
ISS-Studio: A Prototype for a User-Friendly Tool for Designing Interactive Experiments in Problem Solving Environments
In Problem Solving Environments (PSE), Interactive Simulation Systems (ISS) are an important interactive mode for studying complex scientific problems. But efficient and user-friendly tools for designing inter...
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Chapter and Conference Paper
A Versatile Simulation Model for Hierarchical Treecodes
We present here a performance model which simulates different versions of the hierarchical treecode on different computer architectures, including hybrid architectures, where a parallel distributed general pur...
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Chapter and Conference Paper
A Simulation Environment for Job Scheduling on Distributed Systems
In this paper we present a simulation environment for the study of hierarchical job scheduling on distributed systems. The environment provides a multi-level mechanism to simulate various types of jobs. An exe...
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Chapter and Conference Paper
AG-IVE: An Agent Based Solution to Constructing Interactive Simulation Systems
An Interactive Simulation System (ISS) allows a user to interactively explore simulation results and modify the parameters of the simulation at run-time. An ISS is commonly implemented as a distributed system....
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Chapter and Conference Paper
Distributed Simulation of Silicon-Based Film Growth
We present a numerical scheme, grid generation and associated parallel algorithm for the simulation of silicon-based film growth in plasma enhanced chemical vapor deposition reactors. An MPI-based computing en...
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Chapter and Conference Paper
Accuracy of 2D Pulsatile Flow in the Lattice Boltzmann BGK Method
We present detailed analysis of the accuracy of the lattice Boltzmann BGK (LBGK) method in simulating oscillatory flow in a two dimensional channel. Flow parameters such as velocity and shear stress have been ...
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Chapter and Conference Paper
N-Body Simulation on Hybrid Architectures
N-body codes are routinely used for simulation studies of physical systems, e. g. in the fields of computational astrophysics and molecular dynamics. Typically, they require only a moderate amount of run-time m.....
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Chapter and Conference Paper
Cellular Automata as a Mesoscopic Approach to Model and Simulate Complex Systems
We discuss the cellular automata approach and its extensions, the lattice Boltzmann and multiparticle methods. The potential of these techniques is demonstrated in the case of modeling complex systems. In part...
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Chapter and Conference Paper
Experiments with Migration of Message-Passing Tasks
The combined computing capacity of the workstations that are present in many organisations nowadays is often under-utilised, as the performance for parallel programs is unpredictable. Load balancing through dy...
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Chapter and Conference Paper
Performance Analysis of Parallel N-Body Codes
N-body codes are routinely exploited for simulation studies of physical systems, e.g. in the fields of Computational Astrophysics and Molecular Dynamics. Typically, they require only a moderate amount of run-ti.....
