-
Article
Exact solutions to Ernst-like equation in (2+2) Hamiltonian reduction
We apply the method of Hamiltonian reduction without isometry as a way to find exact solutions to Einstein’s equations. To find exact solutions, we introduce two spatial Killing vector fields to the Einstein’s...
-
Article
Open AccessGlobal carrier frequency and predicted genetic prevalence of patients with pathogenic sequence variants in autosomal recessive genetic neuromuscular diseases
Genetic neuromuscular diseases are clinically and genetically heterogeneous genetic disorders that primarily affect the peripheral nerves, muscles, and neuromuscular junctions. This study aimed to identify pat...
-
Article
Open AccessAnalytic non-Abelian gravitating solitons in the Einstein–Yang–Mills–Higgs theory and transitions between them
Two analytic examples of globally regular non-Abelian gravitating solitons in the Einstein–Yang–Mills–Higgs theory in (3 + 1)-dimensions are presented. In both cases, the space-time geometries are of the Naria...
-
Article
Open AccessClinical impact of estradiol/testosterone ratio in patients with acute ischemic stroke
Sex hormones may be associated with a higher incidence of ischemic stroke or stroke-related events. In observational studies, lower testosterone concentrations are associated with infirmity, vascular disease, ...
-
Article
Open AccessGravitating superconducting solitons in the (3+1)-dimensional Einstein gauged non-linear \(\sigma \) -model
In this paper, we construct the first analytic examples of \((3+1)\) ( ...
-
Article
Open AccessMeronic Einstein-Yang-Mills black hole in 5D and gravitational spin from isospin effect
We construct an analytic black hole solution in SU(2) Einstein-Yang-Mills theory in five dimensions supporting a Meron field. The gauge field is proportional to a pure gauge and has a non-trivial topological c...
-
Article
Open AccessAnalytic crystals of solitons in the four dimensional gauged non-linear sigma model
The first analytic topologically non-trivial solutions in the (3 + 1)-dimensional gauged non-linear sigma model representing multi-solitons at finite volume with manifest ordered structures generating their ow...
-
Article
Alteration of microRNA 340-5p and Arginase-1 Expression in Peripheral Blood Cells during Acute Ischemic Stroke
Acute stroke alters the systemic immune response as can be observed in peripheral blood; however, the molecular mechanism by which microRNA (miRNA) regulates target gene expression in response to acute stroke ...
-
Article
Open AccessThe novel hsa-miR-12528 regulates tumourigenesis and metastasis through hypo-phosphorylation of AKT cascade by targeting IGF-1R in human lung cancer
Lung cancer cases are increasing yearly; however, few novel therapeutic strategies for treating this disease have been developed. Here the dysregulation between microRNAs and oncogenes or tumour-suppressor gen...
-
Article
Open AccessInterleukin-1 receptor antagonist-mediated neuroprotection by umbilical cord-derived mesenchymal stromal cells following transplantation into a rodent stroke model
The human umbilical cord is a promising source of mesenchymal stromal cells (MSCs). Intravenous administration of human umbilical cord-derived MSCs (IV-hUMSCs) showed a favorable effect in a rodent stroke mode...
-
Article
Open AccessInterplay between 3′-UTR polymorphisms in the methylenetetrahydrofolate reductase (MTHFR) gene and the risk of ischemic stroke
Stroke incidence is a multifactorial disease and especially hyperhomocysteinemia is associated with a higher risk of stroke. Previous studies have reported a folate metabolism disorder associated with the MTHFR g...
-
Article
Open AccessHuman-to-mouse prion-like propagation of mutant huntingtin protein
Huntington’s disease (HD) is an autosomal dominant neurodegenerative disorder of the central nervous system (CNS) that is defined by a CAG expansion in exon 1 of the huntingtin gene leading to the production o...
-
Article
Predisposing roles of paraoxonase-1 genetic variants in Korean ischemic stroke patients
Paraoxonase-1 (PON1), a high-density lipoprotein (HDL)-associated enzyme, is involved in the metabolism and detoxification of insecticides and pesticides. The aims of this study were to evaluate the role of PON1
-
Article
Open AccessThe GC + CC genotype at position -418 in TIMP-2 promoter and the -1575GA/-1306CC genotype in MMP-2is genetic predisposing factors for prevalence of moyamoya disease
To investigate the association of single-nucleotide polymorphisms (SNPs) in matrix metalloproteinases (MMPs)-2, -3, and -9 and tissue inhibitor of metalloproteinase (TIMP)-2 with moyamoya disease (MMD). We con...
-
Article
Open AccessContralaterally transplanted human embryonic stem cell-derived neural precursor cells (ENStem-A) migrate and improve brain functions in stroke-damaged rats
The transplantation of neural precursor cells (NPCs) is known to be a promising approach to ameliorating behavioral deficits after stroke in a rodent model of middle cerebral artery occlusion (MCAo). Previous ...
-
Article
Analysis and design of frequency selectivity by layered EBG and metamaterial structure
This paper analyzes and designs the electromagnetic band gap (EBG) geometry and metamaterial structure as periodically layered media to have the frequency selectivity showing bandpass and bandstop effects in m...
-
Article
Open AccessPredictive value of circulating interleukin-6 and heart-type fatty acid binding protein for three months clinical outcome in acute cerebral infarction: multiple blood markers profiling study
There is no single blood marker for predicting the prognosis in ischemic stroke. A combination of multiple blood markers may enhance the ability to predict long-term outcome following ischemic stroke.
-
Article
Association of kinase insert domain receptor (KDR -604, 1192, and 1719) polymorphisms with cerebral white matter lesions
Kinase insert domain receptor (KDR) gene polymorphisms are associated with coronary artery lesions. The aims of this study were to evaluate the role of KDR polymorphisms in patients susceptible t...
