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Article
Association of genetic variants of RNF213 with ischemic stroke risk in Koreans
Large artery disease (LAD), cardioembolism (CE), and small vessel disease (SVD) are well-established causes of ischemic stroke. Although a founder variant of RNF213 has been regarded a genetic susceptibility for ...
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Article
Alteration of microRNA 340-5p and Arginase-1 Expression in Peripheral Blood Cells during Acute Ischemic Stroke
Acute stroke alters the systemic immune response as can be observed in peripheral blood; however, the molecular mechanism by which microRNA (miRNA) regulates target gene expression in response to acute stroke ...
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Article
Association study of miR-146a, miR-149, miR-196a2, and miR-499 polymorphisms with venous thromboembolism in a Korean population
Despite much progress in microRNA (miRNA) research, information regarding the association between miRNAs and venous thromboembolism (VTE), especially in Asian patients, remains limited. This case-control study...
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Article
Open AccessInterleukin-1 receptor antagonist-mediated neuroprotection by umbilical cord-derived mesenchymal stromal cells following transplantation into a rodent stroke model
The human umbilical cord is a promising source of mesenchymal stromal cells (MSCs). Intravenous administration of human umbilical cord-derived MSCs (IV-hUMSCs) showed a favorable effect in a rodent stroke mode...
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Article
Open AccessInterplay between 3′-UTR polymorphisms in the methylenetetrahydrofolate reductase (MTHFR) gene and the risk of ischemic stroke
Stroke incidence is a multifactorial disease and especially hyperhomocysteinemia is associated with a higher risk of stroke. Previous studies have reported a folate metabolism disorder associated with the MTHFR g...
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Article
Predisposing roles of paraoxonase-1 genetic variants in Korean ischemic stroke patients
Paraoxonase-1 (PON1), a high-density lipoprotein (HDL)-associated enzyme, is involved in the metabolism and detoxification of insecticides and pesticides. The aims of this study were to evaluate the role of PON1
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Article
Open AccessIntoxication by angel’s trumpet: case report and literature review
Brugmansia, commonly referred to as angel’s trumpet (AT), has been become popular in Korea as an ornamental shrub. However, it is not generally known by the public that this plant contains tropane alkaloids, and ...
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Article
Open AccessPredictive value of circulating interleukin-6 and heart-type fatty acid binding protein for three months clinical outcome in acute cerebral infarction: multiple blood markers profiling study
There is no single blood marker for predicting the prognosis in ischemic stroke. A combination of multiple blood markers may enhance the ability to predict long-term outcome following ischemic stroke.
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Article
Association of kinase insert domain receptor (KDR -604, 1192, and 1719) polymorphisms with cerebral white matter lesions
Kinase insert domain receptor (KDR) gene polymorphisms are associated with coronary artery lesions. The aims of this study were to evaluate the role of KDR polymorphisms in patients susceptible t...
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Article
Evaluation of ictal brain SPET using statistical parametric map** in temporal lobe epilepsy
An automated voxel-based analysis of brain images using statistical parametric map** (SPM) is accepted as a standard approach in the analysis of activation studies in positron emission tomography and functi...
