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Article
The AMPK–Parkin axis negatively regulates necroptosis and tumorigenesis by inhibiting the necrosome
The receptor-interacting serine/threonine-protein kinases RIPK1 and RIPK3 play important roles in necroptosis that are closely linked to the inflammatory response. Although the activation of necroptosis is wel...
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Article
WSB1 overcomes oncogene-induced senescence by targeting ATM for degradation
Oncogene-induced senescence (OIS) or apoptosis through the DNA-damage response is an important barrier of tumorigenesis. Overcoming this barrier leads to abnormal cell proliferation, genomic instability, and c...