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  1. Article

    WSB1 overcomes oncogene-induced senescence by targeting ATM for degradation

    Oncogene-induced senescence (OIS) or apoptosis through the DNA-damage response is an important barrier of tumorigenesis. Overcoming this barrier leads to abnormal cell proliferation, genomic instability, and c...

    Jung ** Kim, Seung Baek Lee, Sang-Yeop Yi, Sang-Ah Han, Sun-Hyun Kim in Cell Research (2017)

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    Article

    Condensed chromatin staining of CKAP2 as surrogate marker for mitotic figures

    Proliferation activity has long been known to be one of the strongest prognostic factors in many different cancers. Nevertheless, microscopic evaluation of mitotic figures remains time-consuming and, furthermo...

    Han-Seong Kim, Yong-Bock Choi, Jung-Hwa Lee in Journal of Cancer Research and Clinical On… (2012)

  3. Article

    Open Access

    High dose concentration administration of ascorbic acid inhibits tumor growth in BALB/C mice implanted with sarcoma 180 cancer cells via the restriction of angiogenesis

    To test the carcinostatic effects of ascorbic acid, we challenged the mice of seven experimental groups with 1.7 × 10-4 mol high dose concentration ascorbic acid after intraperitoneal administrating them with sar...

    Chang-Hwan Yeom, Gunsup Lee, **-Hee Park, Jaelim Yu in Journal of Translational Medicine (2009)