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    Chapter

    BRCA and Breast Cancer-Related High-Penetrance Genes

    Genetic susceptibility explains 5–10% of all breast cancer cases. High-penetrance breast cancer susceptibility genes deliberate a greater than tenfold relative risk of breast cancer. BRCA1 and BRCA2 genes are the...

    Sang-Ah Han, Sung-Won Kim in Translational Research in Breast Cancer (2021)

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    Article

    The AMPK–Parkin axis negatively regulates necroptosis and tumorigenesis by inhibiting the necrosome

    The receptor-interacting serine/threonine-protein kinases RIPK1 and RIPK3 play important roles in necroptosis that are closely linked to the inflammatory response. Although the activation of necroptosis is wel...

    Seung Baek Lee, Jung ** Kim, Sang-Ah Han, Yingfang Fan, Li-Sha Guo in Nature Cell Biology (2019)

  3. Article

    WSB1 overcomes oncogene-induced senescence by targeting ATM for degradation

    Oncogene-induced senescence (OIS) or apoptosis through the DNA-damage response is an important barrier of tumorigenesis. Overcoming this barrier leads to abnormal cell proliferation, genomic instability, and c...

    Jung ** Kim, Seung Baek Lee, Sang-Yeop Yi, Sang-Ah Han, Sun-Hyun Kim in Cell Research (2017)

  4. Article

    Open Access

    Surgical outcomes of robotic thyroidectomy vs. conventional open thyroidectomy for papillary thyroid carcinoma

    The purpose of this study was to compare the surgical outcomes of robotic thyroidectomy (RT) using bilateral axillo-breast approach (BABA) with conventional open thyroidectomy (OT) in papillary thyroid carcino...

    Jeong Nam Cho, Won Seo Park, Sun Young Min in World Journal of Surgical Oncology (2016)

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    Article

    Solitary fibrous tumor of the breast: a case report and review of the literature

    Solitary fibrous tumors (SFTs) are rare mesenchymal neoplasms that can be benign or malignant. SFTs have been most often documented in the pleura. Recently, involvement of extrapleural sites such as the abdome...

    Sun Jung Rhee, Jung Kyu Ryu, Sang-Ah Han, Kyu Yeoun Won in Journal of Medical Ultrasonics (2016)

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    Article

    The prevalence and spectrum of BRCA1 and BRCA2 mutations in Korean population: recent update of the Korean Hereditary Breast Cancer (KOHBRA) study

    The Korean Hereditary Breast Cancer (KOHBRA) study was established to evaluate the prevalence and spectrum of BRCA1/2 mutations in Korean breast cancer patients at risk for hereditary breast and ovarian cancer. A...

    Eunyoung Kang, Moon-Woo Seong, Sue K. Park in Breast Cancer Research and Treatment (2015)

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    Article

    The Protective Effect of Parity in Hormone Receptor-Positive, Ki-67 Expressing Breast Cancer

    Epidemiologic studies showed that the experience of pregnancy is associated with a reduced risk of breast cancer. We hypothesized that parity may differentially be associated with the development of invasive ...

    Se Kyung Lee, Seok Won Kim, Sang-Ah Han, Won Ho Kil in World Journal of Surgery (2014)

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    Article

    The prevalence of BRCA mutations among familial breast cancer patients in Korea: results of the Korean Hereditary Breast Cancer study

    The primary aim of this study was to estimate the prevalence of BRCA1/2 mutations among familial breast cancer (BC) patients in Korea. We analyzed 775 familial BC patients who were enrolled in the Korean Heredita...

    Sang-Ah Han, Sung-Won Kim, Eunyoung Kang, Sue K. Park, Sei-Hyun Ahn in Familial Cancer (2013)

  9. No Access

    Article

    Complementary and alternative medicine use and assessment of quality of life in Korean breast cancer patients: a descriptive study

    The worldwide use of complementary and alternative medicine (CAM) among cancer patients has increased, with breast cancer patients being more likely to use CAM compared with any other cancer patients. However,...

    Eunyoung Kang, Eun Joo Yang, Sun-Mi Kim, Il Yong Chung in Supportive Care in Cancer (2012)

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    Article

    Comparison of immunologic outcomes of laparoscopic vs open approaches in clinical stage III colorectal cancer

    Improved survival in patients with stage III colon cancer after a laparoscopic colectomy (LC) has been reported by Lacy et al. (Lancet 359:2224–2229, 6), and preserved immunity was suggested as the reason for the...

    Sang-Ah Han, Woo Yong Lee, Chi-Min Park in International Journal of Colorectal Disease (2010)