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  1. No Access

    Article

    Gene Expression Profiling as a New Real-Time Assay in Human Biomonitoring of Waste-to-Energy Plant Workers

    Exposure to heavy metals represents one of the most important risk factors for the health of incinerator workers. Indeed, heavy metals can determine increased generation of reactive oxygen species (ROS). In th...

    Alessio Balzerano, Federica Gevi, Stefano Nisi in Biological Trace Element Research (2023)

  2. No Access

    Protocol

    Untargeted Metabolomics of Plant Leaf Tissues

    Untargeted metabolomics is a useful approach for the simultaneous analysis of a vast array of compounds from a single extract. Metabolomic profiling is the relative multi-parallel quantification of a mixture o...

    Federica Gevi, Giuseppina Fanelli, Lello Zolla in High-Throughput Metabolomics (2019)

  3. Article

    Open Access

    Metabolomics and proteomics reveal drought-stress responses of leaf tissues from spring-wheat

    To reveal the integrative biochemical networks of wheat leaves in response to water deficient conditions, proteomics and metabolomics were applied to two spring-wheat cultivars (Bahar, drought-susceptible; Kavir,...

    Anna Michaletti, Mohammad Reza Naghavi, Mahmoud Toorchi, Lello Zolla in Scientific Reports (2018)

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    Chapter

    What Can Small Molecules Tell Us About Cold Stress Tolerance in Plants?

    Plants display a wide capacity range to survive cold and freezing conditions. Indeed, they are able to sense low, non-freezing temperatures and activate processes that lead to an increase in freezing tolerance...

    Valentina Longo, Mohsen Janmohammadi, Lello Zolla in Cold Tolerance in Plants (2018)

  5. Article

    Open Access

    CDK1 phosphorylates WRN at collapsed replication forks

    Regulation of end-processing is critical for accurate repair and to switch between homologous recombination (HR) and non-homologous end joining (NHEJ). End resection is a two-stage process but very little is k...

    Valentina Palermo, Sara Rinalducci, Massimo Sanchez in Nature Communications (2016)

  6. No Access

    Chapter and Conference Paper

    Untargeted metabolomic analyses open new scenarios in post mortem pig muscles: Casertana and Large White

    Post mortem metabolism of pig muscles represents a pivotal area of research, in that pig meat quality is largely influenced by biochemical changes arising soon after slaughter. Metabolic rate and, ...

    Cristina Marrocco, Angelo D’Alessandro, Sara Rinalducci in Farm animal proteomics 2013 (2013)

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    Article

    Changes in morphology, cell wall composition and soluble proteome in Rhodobacter sphaeroides cells exposed to chromate

    The response of the carotenoidless Rhodobacter sphaeroides mutant R26 to chromate stress under photosynthetic conditions is investigated by biochemical and spectroscopic measurements, proteomic analysis and cell ...

    Francesca Italiano, Sara Rinalducci, Angela Agostiano, Lello Zolla in BioMetals (2012)

  8. No Access

    Protocol

    Combinatorial Peptide Ligand Libraries to Discover Liver Disease Biomarkers in Plasma Samples

    High-abundance proteins present in blood plasma make the detection of low-abundance proteins extremely difficult by proteomics technology. Hexapeptide combinatorial ligand libraries can be used to investigate ...

    Gian Maria D’Amici, Anna Maria Timperio, Sara Rinalducci, Lello Zolla in Liver Proteomics (2012)

  9. No Access

    Article

    Depletion of hemoglobin and carbonic anhydrase from erythrocyte cytosolic samples by preparative clear native electrophoresis

    Proteomic analysis of red cells is compromised by the presence of high-abundance proteins (hemoglobin and carbonic anhydrase-1), which completely obscure low-abundance species. The depletion method presented h...

    Gian Maria D'Amici, Sara Rinalducci, Lello Zolla in Nature Protocols (2012)

  10. No Access

    Chapter and Conference Paper

    Effect of Cobalt Ions on the Soluble Proteome of a Rhodobacter sphaeroides Carotenoidless Mutant

    Rhodobacter sphaeroides strain R26.1 showed tolerance to Co2+ ions, up to 10 mM concentration. Interestingly the bacteriochlorophyll biosynthesis was found to decrease upon addition of such metal i...

    Francesca Italiano, Francesco Pisani in Photosynthesis. Energy from the Sun (2008)