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Article
Open AccessSimulated microgravity induces a cellular regression of the mature phenotype in human primary osteoblasts
Decreased mechanical loading on bones, such as prolonged bed rest and microgravity during space flights, leads to the development of an osteoporotic-like phenotype. Although osteoblast hypo-functionality is re...
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Article
Open AccessMetabolomics and proteomics reveal drought-stress responses of leaf tissues from spring-wheat
To reveal the integrative biochemical networks of wheat leaves in response to water deficient conditions, proteomics and metabolomics were applied to two spring-wheat cultivars (Bahar, drought-susceptible; Kavir,...
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Article
Open AccessEffects of microgravity on osteoblast mitochondria: a proteomic and metabolomics profile
The response of human primary osteoblasts exposed to simulated microgravity has been investigated and analysis of metabolomic and proteomic profiles demonstrated a prominent dysregulation of mitochondrion home...
