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Article
Histone acetyl transferases: a role in DNA repair and DNA replication
In eukaryotic cells DNA is associated with proteins to form a complex known as chromatin. The dominant proteins within this chromatin complex are the histones, which are subject to a wide variety of covalent a...
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Article
Transcription coactivator p300 binds PCNA and may have a role in DNA repair synthesis
The transcriptional coactivator p300 interacts with many transcription factors that participate in a broad spectrum of biological activities, such as cellular differentiation, homeostasis and growth control1,2. M...