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Open AccessInflammation, oxidative stress, glomerular filtration rate, and albuminuria in elderly men: a cross-sectional study
The role of inflammation and oxidative stress in mild renal impairment in the elderly is not well studied. Accordingly, we aimed at investigating the associations between estimated glomerular filtration rate (...
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Carbon Tetrachloride-Induced Hepatotoxicity: A Classic Model of Lipid Peroxidation and Oxidative Stress
Carbon tetrachloride (CCl4)-induced lipid peroxidation and liver injury is a classic experimental model for comprehending the cellular mechanisms behind oxidative injury, and further estimating the therapeutic po...
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An Experimental Model of Myocardial and Cerebral Global Ischemia and Reperfusion
Despite many programs aimed at better immediate care of cardiac arrest victims, the subsequent mortality rate remains high, with myocardial and central nervous system injuries as the most common causes of deat...
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Oxidative Stress in Animal Models with Special Reference to Experimental Porcine Endotoxemia
Animal experiments offer a unique possibility to tailor study design and to standardize the experiment in a way that allows us to repeat challenges, monitoring and interventions according to scientific rationa...
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Open AccessMetabolic Effects of Krill Oil are Essentially Similar to Those of Fish Oil but at Lower Dose of EPA and DHA, in Healthy Volunteers
The purpose of the present study is to investigate the effects of krill oil and fish oil on serum lipids and markers of oxidative stress and inflammation and to evaluate if different molecular forms, triacylgl...
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Bioactive eicosanoids: Role of prostaglandin F2α and F2-isoprostanes in inflammation and oxidative stress related pathology
Oxidative stress and inflammation are supposed to be the key players of several acute and chronic diseases, and also for progressive aging process. Eicosanoids, especially prostaglandin F2α (PGF2α) and F2-isopros...
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Open AccessIncreased isoprostane and prostaglandin are prominent in neurons in Alzheimer disease
Inflammation and oxidative stress are both involved in the pathogenesis of Alzheimer disease and have been shown to be reciprocally linked. One group of molecules that have been directly associated with inflam...
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CLA and body weight regulation in humans
CLA comprises a group of unsaturated FA isomers with a variety of biological effects in experimental animals. CLA reduces body fat accumulation in animal models and has been suggested to have significant effec...
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Acute elevations of medium-and long-chain fatty acids have different impacts on endothelium-dependent vasodilation in humans
It has previously been shown that acute elevation of long-chain fatty acids (LCFA) impairs endothelium-dependent vasodilation (EDV) in humans. In this study, we tested the hypothesis that an elevation of both ...
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Endothelial vasodilatory function is predicted by circulating apolipoprotein B and HDL in healthy humans
Endothelium-dependent vasodilation (EDV), LDL particle size, and antibodies against oxidized LDL (oxLDLab) have been shown to be related to the development of atherosclerosis and cardiovascular disease. In thi...
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Cardiac and vascular structure and function are related to lipid peroxidation and metabolism
The present study investigated possible relationships between left ventricular mass, intima-media thickness of the carotid artery (IMT), total arterial compliance, and lipid status in a population sample of 58...
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Effects of dietary phenolic compounds on tocopherol, cholesterol, and fatty acids in rats
The effects of the phenolic compounds butylated hydroxytoluene (BHT), sesamin (S), curcumin (CU), and ferulic acid (FA) on plasma, liver, and lung concentrations of α- and γ-tocopherols (T), on plasma and live...
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Green tea extract decreases plasma malondialdehyde concentration but does not affect other indicators of oxidative stress, nitric oxide production, or hemostatic factors during a high-linoleic acid diet in healthy females
Background: Green tea contains polyphenolic catechins which can act as antioxidants and thus decrease the risk for cardiovascular diseases.
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Green tea extract does not affect urinary markers of lipid peroxidation or thromboxane or nitric oxide synthesis during a high-linoleic acid diet in healthy females
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Metabolites of PGF2α in Blood Plasma and Urine as Parameters of PGF2α Release in Cattle
The metabolism of PGF2α in cattle results initially in the formation of 15-keto-13,14-dihydro-PGF2α (15-ketodihydro-PGF2α) and later the 11-ketotetranor PGF metabolites. Both types of metabolites appear in the pe...
