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Article
Open AccessEvaluation of the impact of genetic polymorphisms in glutathione-related genes on the association between methylmercury or n-3 polyunsaturated long chain fatty acids and risk of myocardial infarction: a case-control study
The n-3 polyunsaturated fatty acids eicosapentaenoic acid and docosahexaenoic acid, which are present in fish, are protective against myocardial infarction. However, fish also contains methylmercury, which inf...
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Article
Open AccessAssociations between estimated fatty acid desaturase activities in serum lipids and adipose tissue in humans: links to obesity and insulin resistance
Fatty acid composition of serum lipids and adipose tissue triacylglycerols (AT-TAG) partly reflect dietary fatty acid intake. The fatty acid composition is, besides the diet, also influenced by desaturating en...
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Article
Open AccessStroke and plasma markers of milk fat intake – a prospective nested case-control study
Dairy products are high in saturated fat and are traditionally a risk factor for vascular diseases. The fatty acids 15:0 and 17:0 of plasma lipids are biomarkers of milk fat intake. The aim of the present stud...
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Article
PASSCLAIM1—Body weight regulation, insulin sensitivity and diabetes risk
Insulin sensitivity is a key function in human metabolism because it has a crucial role in the development of disease that are increasingly common in modern society. Impaired insulin sensitivity is an importan...
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Article
CLA and body weight regulation in humans
CLA comprises a group of unsaturated FA isomers with a variety of biological effects in experimental animals. CLA reduces body fat accumulation in animal models and has been suggested to have significant effec...
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Article
Acute elevations of medium-and long-chain fatty acids have different impacts on endothelium-dependent vasodilation in humans
It has previously been shown that acute elevation of long-chain fatty acids (LCFA) impairs endothelium-dependent vasodilation (EDV) in humans. In this study, we tested the hypothesis that an elevation of both ...
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Article
The types of circulating fatty acids influence vascular reactivity
The objective of this study was to investigate the relationship between the composition of FA in serum lipids, a marker of dietary fat intake, and vascular reactivity using a combination of cross-sectional and...
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Article
Endothelial vasodilatory function is predicted by circulating apolipoprotein B and HDL in healthy humans
Endothelium-dependent vasodilation (EDV), LDL particle size, and antibodies against oxidized LDL (oxLDLab) have been shown to be related to the development of atherosclerosis and cardiovascular disease. In thi...
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Article
Cardiac and vascular structure and function are related to lipid peroxidation and metabolism
The present study investigated possible relationships between left ventricular mass, intima-media thickness of the carotid artery (IMT), total arterial compliance, and lipid status in a population sample of 58...
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Article
Conjugated linoleic acid supplementation in humans—metabolic effects
Supplementation with conjugated linoleic acid (CLA) induces a number of physiological effects in experimental animals, including reduced body fat content, decreased aortic lipid deposition, and improved serum ...
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Article
Effects of dietary phenolic compounds on tocopherol, cholesterol, and fatty acids in rats
The effects of the phenolic compounds butylated hydroxytoluene (BHT), sesamin (S), curcumin (CU), and ferulic acid (FA) on plasma, liver, and lung concentrations of α- and γ-tocopherols (T), on plasma and live...
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Article
Lipoprotein composition and serum cholesterol ester fatty acids in nonwesternized melanesians
In this study, the relationships between dietary fat [as measured by serum cholesterol ester fatty acids (CE-FA)], age, smoking, body mass index, and serum lipids were analyzed in 151 subsistence horticultural...
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Chapter and Conference Paper
Impaired Fatty Acid Incorporation Into Adipose Tissue (Fiat) in Hypertriglyceridemia. Effect of Intravenous Fat Infusion on Fiat
In the development of hypertriglyceridemia (HTG) two general mechanisms may be operating: 1. Increased production of triglycerides (TG) from the liver, 2. Decreased removal of TG from the blood to peripheral tiss...