-
Article
Open AccessAvapritinib-based SAR studies unveil a binding pocket in KIT and PDGFRA
Avapritinib is the only potent and selective inhibitor approved for the treatment of D842V-mutant gastrointestinal stromal tumors (GIST), the most common primary mutation of the platelet-derived growth factor ...
-
Chapter
Genetic Aspects of Cell Line Development from a Synthetic Biology Perspective
Animal cells can be regarded as factories for the production of relevant proteins. The advances described in this chapter towards the development of cell lines with higher productivity capacities, certain meta...
-
Article
Magneto-optical study of grain boundaries, interfaces and grain boundary networks in YBaCuO
Using quantitative magneto-optics and an inversion scheme of Biot-Savart’s law the local current carrying capability of various types of grain boundaries (GB’s) and interfaces in YBaCuO thin films and bulk mat...
-
Article
Nanostructuring of Multilayers by a Thermally Driven Self Assembling Process
Multilayers consisting of two immiscible components (e.g. Fe/Ag Fe/Au or Ni/NiO) could by transformed by an annealing process into a nanostructured system of non statistically distributed nearly spherical part...
-
Article
Magnetism in V-/Mn-doped ZnO layers fabricated on sapphire
Do** ZnO with transition metals (TM) is an obvious approach to produce diluted magnetic semiconductors for magnetoelectronic and spintronic applications. We have carried out experimental studies on the fabri...
-
Chapter and Conference Paper
Magneto Optical Imaging of Small Angle Grain Boundaries on Different Bi-Crystalline Substrates
With quantitative high resolution magneto-optical imaging the percolative nature of magnetisation currents in granular coated conductors has been studied. As a model system for these types of grain boundaries ...
-
Article
Nanostructuring of Multilayers by a Thermally Driven Self Assembling Process
Multilayers consisting of two immiscible components (e.g. Fe/Ag Fe/Au or Ni/NiO) could by transformed by an annealing process into a nanostructured system of non statistically distributed nearly spherical part...
-
Article
Variable-azimuth laser ablation: principles and application for film deposition on long tubes and tapes
A new development of the pulsed laser ablation (PLA) technique based on variable azimuth ablation (VAA) is reported. The VAA itself is based on periodic variations of the azimuth of the laser beam relative to...
-
Article
Biaxially Textured Buffer Layers on Large-Area Polycrystalline Substrates
Biaxially textured yttria stabilized zirconia (YSZ) buffer layers were deposited on long polycrystalline metallic tapes by an ion-beam-assisted deposition process (IBAD) to serve as templates for high-current ...
-
Chapter
YBaCuO-Coated High-Jc Conductors
YBaCuO thick films possess the potential to become HTS conductors of the second generation. Technical polycrystalline substrates, which can be metallic or nonmetallic, were used in the form of tapes, tubes or ...
-
Chapter
Investigation Strategies on Contaminated Sites: Sampling and Analyses
The multitude of possibly dangerously contaminated sites -abandoned landfills, former industrial sites, etc.- makes it necessary to develop economic methods of investigation in cases of suspected contamination...
-
Chapter
Untersuchungsstrategien für Altlastverdachtsflächen: Beprobung und Analytik
In Anbetracht der Vielzahl möglicherweise bedenklich belasteter Altablagerungen und Altstandorte ist es erforderlich, ökonomische Verfahren zur Untersuchung von Verdachtsflächen zu entwickeln, die gleichwohl h...
-
Article
Quantification of volatile sulfur compounds related to the corrosion of concrete sewers
Es wird ein gas-chromatographisches Verfahren zur Bestimmung flüchtiger Schwefelverbindungen beschrieben, die mittelbar an der Substratbildung für Schwefelsäure bildende Thiobazillen beteiligt sind. Flüchtige ...
-
Chapter and Conference Paper
Klinische Anwendbarkeit der histologischen Klassifikation
Die malignen Ovarialbildungen sind so vielfältig, daß die Ovarialtumoren auch dann nicht als Einheit betrachtet werden können, wenn es um therapeutische Maßnahmen geht. Aus diesem Grunde gilt es, Selektionskri...
-
Article
Kurzvorträge und Poster zum Thema Schwangerschaftsabbruch
-
Article
Die histologische Reaktion des Endometrium auf lokal applizierte Gestagene
To study the histologic changes produced by a new type of progesterone-medicated intrauterine device we examined the endometria of six hysterectomy specimens and one complete curettage. After being in place fo...
