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Article
Threonine metabolism in Japanese quail liver
In general, threonine is metabolized by reaction catalyzed by threonine-3-dehydrogenase (TDH), threonine dehydratase (TH) or threonine aldolase (TA). The activities of these three enzymes were compared in the ...
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Article
Threonine is the best substrate for D-lactate formation in octopus tentacle
Carbon sources for D-lactate and enzyme activities related to D-lactate formation were investigated using cell-free homogenates of Octopus vulgaris tentacle tissue. The results are as follows: a) The best precurs...
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Article
Spinal anesthesia hypotension in elective cesarean section in parturients wearing extra-strong compression stockings
We have routinely applied an extra-strong graduated compression stocking to cesarean section patients to reduce the incidence of spinal anesthesia hypotension. Because bupivacaine has recently become available...
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Article
Effects of heat-treatment on electrochemical behavior
The polyacenic semiconductive (PAS) material is a typical amorphous carbon prepared by pyrolysis of phenolformaldehyde resin, and is actually utilized as anode of high-capacity rechargeable batteries. In this ...
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Article
Extra-strong graduated compression stocking reduces usage of vasopressor agents during spinal anesthesia for cesarean section
Because a standard type of graduated compression stocking is not effective for the prevention of spinal anesthesia hypothension during cesarean section, we have used an extra-strong type of graduated compressi...
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Article
A Japanese family with autosomal dominant growth hormone deficiency
We report a 1-year-old Japanese boy and his father with isolated growth hormone deficiency II. In both cases, a G → A transition of the first base of the donor splice site of intron 3 of the growth hormone-1 ...
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Article
Prediction of drug-drug interactions of zonisamide metabolism in humans from in vitro data
Objective: The purposes of this study were to identify the P450 enzyme (CYP) responsible for zonisamide metabolism in humans by using expressed human CYPs and to predict drug interaction...
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Article
Changes in urinary 6β-hydroxycortisol/cortisol ratio after birth in human neonates
Objective: Urinary 6β-hydroxycortisol/cortisol (6β-OHF/C) ratio was measured in human neonates to assess the CYP3A enzyme activity.
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Article
Changes in concentrations of methylglyoxal,d-lactate and glyoxalase activities in liver and plasma of rats fed a 3′-methyl-4-dimethylaminoazobenzene-rich diet
Donryu male albino rats were fed a diet containing 0.064% 3′-methyl-4-dimethylaminoazobenzene (MDAB) for 21 weeks. During the ensuing rat liver carcinogenesis, changes in the concentrations of methylglyoxal,d-lac...
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Article
Changes in levels of glutathione and related compounds and activities of glutathione-related enzymes during rat liver regeneration
The levels of glutathione and glutathione disulfide increased during the regeneration process of rat liver, reaching a maximum (about twice the control value) on day 2 and reverting to the normal level within ...
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Article
The association of the insulin resistance syndrome with impaired glucose tolerance and NIDDM in the Japanese general population: the Hisayama study
To elucidate the risk factors for initiating glucose intolerance, the relevant factors were explored in a cross-sectional survey conducted in a sample population aged 40–79 years old selected from a Japanese c...
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Article
Prevalence of Type 2 (non-insulin-dependent) diabetes mellitus and impaired glucose tolerance in the Japanese general population: the Hisayama study
We determined the population-based prevalence of diabetes mellitus in members of the Japanese community, Hisayama aged 40–79 years old by a 75-g oral glucose tolerance test. The basic population used to calcul...
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Article
Increase ofS-(1,2-dicarboxyethyl)glutathione in regenerating rat liver
Changes in the level ofS-(1,2-dicarboxyethyl)glutathione (DCE-GS) with time were determined during regeneration of rat liver after partial hepatectomy. The DCE-GS level increased in regenerating rat liver, reachi...
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Article
Concentrations ofd-lactate and its related metabolic intermediates in liver, blood, and muscle of diabetic and starved rats
This is a report investigating the methylglyoxal (MG) bypass in animals, by whichd-lactate is produced from triosephosphate via MG. Rats were made diabetic using streptozotocin or starved for 72 h.d-Lactate and v...
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Article
Enhancing effect of S-(1,2-dicarboxyethyl)glutathione on epidermal growth factor-stimulated DNA synthesis in primary cultures of adult rat hepatocytes
A tripeptide S-(1,2-dicarboxyethyl)glutathione (DCE-GS) has been reported to be present in the lens, liver, and heart. Effects of DCE-GS and its derivatives and analogues on hepatocyte deoxyribonucleic acid (DNA)...
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Article
Elemental concentrations in hair of inhabitants of a cadmium-polluted area
To investigate the present situation of inhabitants living in the cadmium-polluted area of Toyama Prefecture, 95 hair samples were analyzed instrumentally by the neutron activation method. The concentrations w...
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Chapter
Elemental Concentrations in Hair of Inhabitants of a Cadmium-Polluted Area
To investigate the present situation of inhabitants living in the cadmium-polluted area of Toyama Prefecture, 95 hair samples were analyzed instramentally by the neutron activation method. The concentrations w...
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Article
Cadmium, copper and zinc concentrations in hair of inhabitants of a cadmium polluted area
To investigate the present situation of inhabitants living in the cadmium polluted area of Toyama Prefecture of Japan, 95 hair samples were analyzed by neutron activation method. The median and the geometric s...
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Article
Catching conditions of a disease with nondestructive activation analysis of hair
In this study, we aimed to recognize the body abnormalities through determining the metallic balance of hair. We determinated multiple elements of patients hair with acute chromium poisoning by burn from the w...
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Article
Comparisons of elemental concentrations in hair of the inhabitants of heavy metal polluted areas with those of normal Japanese
Human hair collected from the mercury, arsenic and cadmium polluted areas has been analysed by instrumental neutron activation method. The concentrations of 27 elements were compared with those of normal Japan...
