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Article
Exendin-4 regulates the expression of the ATP-binding cassette transporter A1 via transcriptional factor PREB in the pancreatic β cell line
Background: PRL regulatory element-binding (PREB) protein is a transcription factor that regulates insulin promoter activity in the rat anterior pituitary. The PREB protein is expressed not only ...
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Article
Prolactin regulatory element binding protein as a potential transcriptional factor for the insulin gene in response to glucose stimulation
Prolactin regulatory element binding (PREB) protein has been identified as a factor that regulates prolactin promoter activity in rat anterior pituitary. PREB is located not only in the anterior pituitary but ...
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Article
Spinal anesthesia hypotension in elective cesarean section in parturients wearing extra-strong compression stockings
We have routinely applied an extra-strong graduated compression stocking to cesarean section patients to reduce the incidence of spinal anesthesia hypotension. Because bupivacaine has recently become available...
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Article
Extra-strong graduated compression stocking reduces usage of vasopressor agents during spinal anesthesia for cesarean section
Because a standard type of graduated compression stocking is not effective for the prevention of spinal anesthesia hypothension during cesarean section, we have used an extra-strong type of graduated compressi...
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Article
Concentrative relationship between polymorphonuclear elastase and urinary trypsin inhibitor in amniotic fluid
In the amniotic fluid, urinary trypsin inhibitor (UTI) seems to inhibit polymorphonuclear elastase (PMNE) activity. The PMNE and UTI concentrations in normal amniotic fluid at 16–20 and 38–40 gestational weeks...
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Article
Serum concentrations of soluble Fas antigen and soluble Fas ligand in mother and newborn
We measured soluble Fas antigen and soluble Fas ligand, which are considered to be an apoptotic substance, in maternal serum, umbilical cord serum and amniotic fluid during cesarean section at full term pregna...
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Article
Time course of activated coagulation time at various sites during continuous haemodiafiltration using nafamostat mesilate
Objective: To determine the adequate site of activated coagulation time (ACT) measurement during continuous haemodiafiltration (CHDF) using nafamostat mesilate. Design: Prospective, cons...
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Article
The Wilms’ tumor gene WT1 is a good marker for diagnosis of disease progression of myelodysplastic syndromes
The Wilms’ tumor gene, WT1, is a tumor marker for leukemic blast cells. The WT1 expression levels were examined for 57 patients with myelodysplastic syndromes (MDS) (refractory anemia (RA), 35; RA with excess ...
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Article
Telomerase activity and cytogenetic changes in chronic myeloid leukemia with disease progression
Progressive telomere shortening is thought to be important in the regulation of cellular senescence and that the upregulation or reactivation of telomerase activity may be a critical if not rate limiting step ...