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  1. No Access

    Article

    Klinefelter Bone Microarchitecture Evolution with Testosterone Replacement Therapy

    Klinefelter Syndrome (KS) patients, defined by a 47 XXY karyotype, have increased risk of fragility fractures. We have assessed bone microarchitecture by high resolution peripheral quantitative CT (HR-pQCT) at...

    A. Piot, I. Plotton, S. Boutroy, J. Bacchetta, S. Ailloud… in Calcified Tissue International (2022)

  2. No Access

    Article

    Operator variability in scan positioning is a major component of HR-pQCT precision error and is reduced by standardized training

    In this study, we determined that operator positioning precision contributes significant measurement error in high-resolution peripheral quantitative computed tomography (HR-pQCT). Moreover, we developed softw...

    S. Bonaretti, N. Vilayphiou, C. M. Chan, A. Yu, K. Nishiyama… in Osteoporosis International (2017)

  3. No Access

    Article

    Clinical cone beam computed tomography compared to high-resolution peripheral computed tomography in the assessment of distal radius bone

    Clinical cone beam computed tomography (CBCT) was compared to high-resolution peripheral quantitative computed tomography (HR-pQCT) for the assessment of ex vivo radii. Strong correlations were found for geome...

    C. de Charry, S. Boutroy, R. Ellouz, F. Duboeuf, R. Chapurlat… in Osteoporosis International (2016)

  4. No Access

    Article

    Reduced bone volumetric density and weak correlation between infection and bone markers in cystic fibrosis adult patients

    In our current adult CF population, low BMD prevalence was only 20 %, lower than that historically described. We found a mild increase of serum RANK-L levels, independent from the bone resorption level. The in...

    D. Gensburger, S. Boutroy, R. Chapurlat, R. Nove-Josserand… in Osteoporosis International (2016)

  5. No Access

    Article

    Left–right differences in the proximal femur’s strength of post-menopausal women: a multicentric finite element study

    The strength of both femurs was estimated in 198 post-menopausal women through subject-specific finite element models. Important random differences between contralateral femurs were found in a significant numb...

    F. Taddei, C. Falcinelli, L. Balistreri, P. Henys… in Osteoporosis International (2016)

  6. No Access

    Article

    Family resemblance of bone turnover rate in mothers and daughters—the MODAM study

    We studied bone turnover markers (BTM) and bone microarchitecture (using high-resolution peripheral quantitative computed tomography (HR-pQCT)) in 171 postmenopausal women and their 210 premenopausal daughters...

    H. Nagy, R. Chapurlat, E. Sornay-Rendu, S. Boutroy, P. Szulc in Osteoporosis International (2015)

  7. No Access

    Article

    The predictive value of trabecular bone score (TBS) on whole lumbar vertebrae mechanics: an ex vivo study

    We investigated the association of trabecular bone score (TBS) with microarchitecture and mechanical behavior of human lumbar vertebrae. We found that TBS reflects vertebral trabecular microarchitecture and is...

    J. P. Roux, J. Wegrzyn, S. Boutroy, M. L. Bouxsein, D. Hans… in Osteoporosis International (2013)

  8. No Access

    Article

    Impaired trabecular and cortical microarchitecture in daughters of women with osteoporotic fracture: the MODAM study

    We investigated the familial resemblance of bone microarchitecture parameters between postmenopausal mothers with fragility fracture and their premenopausal daughters using high-resolution peripheral quantitat...

    H. Nagy, E. Sornay-Rendu, S. Boutroy, N. Vilayphiou, P. Szulc… in Osteoporosis International (2013)

  9. No Access

    Article

    Trabecular bone score improves fracture risk prediction in non-osteoporotic women: the OFELY study

    The use of areal bone mineral density (aBMD) for fracture prediction may be enhanced by considering bone microarchitectural deterioration. Trabecular bone score (TBS) helped in redefining a significant subset ...

    S. Boutroy, D. Hans, E. Sornay-Rendu, N. Vilayphiou… in Osteoporosis International (2013)

  10. No Access

    Article

    Poor bone microarchitecture in older men with impaired physical performance—the STRAMBO study

    In 810 men ≥60 years, poor physical performance of lower limbs was associated with lower areal bone mineral density (aBMD) of total hip and poor bone microarchitecture at the distal tibia (assessed by HR-pQCT)...

    S. Blaizot, S. Boutroy, N. Vilayphiou, S. Boonen… in Osteoporosis International (2012)

  11. No Access

    Article

    Poor Trabecular Microarchitecture at the Distal Radius in Older Men with Increased Concentration of High-Sensitivity C-Reactive Protein—The Strambo Study

    Low-grade inflammation, assessed by serum high-sensitivity C-reactive protein (hsCRP) concentration, is associated with higher fracture risk irrespective of areal bone mineral density (aBMD). We assessed the a...

    T. Rolland, S. Boutroy, N. Vilayphiou, S. Blaizot… in Calcified Tissue International (2012)

  12. No Access

    Article

    Effects of strontium ranelate and alendronate on bone microstructure in women with osteoporosis

    Strontium ranelate appears to influence more than alendronate distal tibia bone microstructure as assessed by high-resolution peripheral quantitative computed tomography (HR-pQCT), and biomechanically relevant...

    R. Rizzoli, R. D. Chapurlat, J.-M. Laroche, M. A. Krieg… in Osteoporosis International (2012)

  13. No Access

    Article

    Poor Trabecular Microarchitecture in Male Current Smokers: The Cross-Sectional STRAMBO Study

    Current smoking (but not past smoking) is associated with higher risk of fracture independent of areal bone mineral density (aBMD); however, the pathophysiologic mechanism underlying this association is not cl...

    P. Szulc, E. Debiesse, S. Boutroy, N. Vilauphiou… in Calcified Tissue International (2011)

  14. No Access

    Article

    Cortical and trabecular architecture are altered in postmenopausal women with fractures

    E. Sornay-Rendu, S. Boutroy, F. Munoz, M. L. Bouxsein in Osteoporosis International (2009)