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  1. No Access

    Article

    Nucleation of DNA repair factors by FOXA1 links DNA demethylation to transcriptional pioneering

    Yongfeng Shang and colleagues report that the pioneering factor FOXA1 associates with DNA repair complexes and regulates DNA demethylation at its genomic targets in a DNA polymerase β–dependent manner. They sh...

    Yu Zhang, Di Zhang, Qian Li, **g Liang, Luyang Sun, **a Yi, Zhe Chen… in Nature Genetics (2016)

  2. Article

    Open Access

    SIRT7 is a histone desuccinylase that functionally links to chromatin compaction and genome stability

    Although SIRT7 is a member of sirtuin family proteins that are described as NAD+-dependent class III histone deacetylases, the intrinsic enzymatic activity of this sirtuin protein remains to be investigated and t...

    Lei Li, Lan Shi, Shangda Yang, Ruorong Yan, Di Zhang, Jianguo Yang… in Nature Communications (2016)

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