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  1. Article

    Open Access

    The Retinoic Acid Receptor-α mediates human T-cell activation and Th2 cytokine and chemokine production

    We have recently demonstrated that all-trans-retinoic acid (ATRA) and 9-cis-retinoic acid (9-cis RA) promote IL-4, IL-5 and IL-13 synthesis, while decreasing IFN-γ and TNF-α expression by activated human T cells ...

    Harry D Dawson, Gary Collins, Robert Pyle, Michael Key, Dennis D Taub in BMC Immunology (2008)

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  2. Article

    Open Access

    Direct and indirect effects of retinoic acid on human Th2 cytokine and chemokine expression by human T lymphocytes

    Vitamin A (VA) deficiency induces a type 1 cytokine response and exogenously provided retinoids can induce a type 2 cytokine response both in vitro and in vivo. The precise mechanism(s) involved in this phenotypi...

    Harry D Dawson, Gary Collins, Robert Pyle, Michael Key, Ashani Weeraratna… in BMC Immunology (2006)

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  3. No Access

    Article

    A comparison study of the climatological air-sea heat fluxes estimated by different computational schemes of bulk formula

    In this paper the different results of estimated air-sea heat fluxes by different computational schemes of bulk formula are researched. The varying results may bring another source of the uncertainties of flux...

    Fu Congbin, Robert Pyle, Fan Huijun in Advances in Atmospheric Sciences (1994)