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Gene therapy of metastatic cancer by in vivo retroviral gene targeting
We have achieved efficient transduction of tumour metastases in vivo by the vascular delivery of retroviral producer cells. Experimental liver metastases in mice were created by intrasplenic injection of tumour c...
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Novel Strategies for Cancer Treatment through Modulation of Proimmune and Proinflammatory Cytokines
The remarkable progress in understanding the molecular basis of the immune system has prompted new strategies for the treatment of experimental and human cancers. In particular, the cloning and identification ...