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Article
Open AccessTop Secrets: long-lived ALPs in top production
We investigate the discovery potential for long-lived particles produced in association with a top-antitop quark pair at the (High-Luminosity) LHC. Compared to inclusive searches for a displaced vertex, top-as...
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Article
Open AccessDisplaced or invisible? ALPs from B decays at Belle II
At colliders, neutral long-lived particles can be detected through displaced decay products or as missing energy. Which search strategy is better depends on the particle’s decay length just as on the detector ...
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Article
Kerr Microscopy Study of Magnetic Phase Transition in Fe49Rh51
Magnetic phase transition in Fe49Rh51 was studied using wide-field Kerr microscopy. In zero magnetic field, temperature dependences of rotation of polarization plane on the sample surface are obtained. The analys...
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Article
Extended evaluation of the efficacy of a proactive forced oscillation technique-based auto-CPAP algorithm
Previous studies revealed substantially varying therapy efficacy of automatic continuous positive airway pressure (APAP) devices in the treatment of obstructive sleep apnea (OSA). We evaluated the efficacy of ...
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Article
TEG-unterstützte Therapie einer Dabigatranüberdosierung bei einem Patienten mit akutem Nierenversagen
Es wird über einen multimorbiden Patienten berichtet, bei dem es durch ein Nierenversagen im Rahmen einer akuten intestinalen Erkrankung zu einer akzidentellen Überdosierung mit Dabigatran und folgender intrap...
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Article
Open AccessThe Refeeding Syndrome revisited: you can only diagnose what you know
The Refeeding Syndrome (RFS) is a serious complication in patients receiving nutrition support after a period of severe malnutrition. We frequently recognize and diagnose the RFS due to increased awareness. Th...
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Article
Open AccessThe role of the cancer stem cell marker CD271 in DNA damage response and drug resistance of melanoma cells
Several lines of evidence have suggested that stemness and acquired resistance to targeted inhibitors or chemotherapeutics are mechanistically linked. Here we observed high cell surface and total levels of ner...
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Article
Open AccessUncoupling of EGFR–RAS signaling and nuclear localization of YBX1 in colorectal cancer
The transcription factor YBX1 can act as a mediator of signals transmitted via the EGFR–RAS–MAPK axis. YBX1 expression has been associated with tumor progression and prognosis in multiple types of cancer. Immu...
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Article
Optical absorption spectra and structures of Ag 6 + and Ag 8 +
This work presents optical photodissociation spectra of the Ag 6 + and the Ag 8 + clusters in ...
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Article
Transgenic expression of oncogenic BRAF induces loss of stem cells in the mouse intestine, which is antagonized by β-catenin activity
Colon cancer cells frequently carry mutations that activate the β-catenin and mitogen-activated protein kinase (MAPK) signaling cascades. Yet how oncogenic alterations interact to control cellular hierarchies ...
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Article
Do doctors know how much nutrition patients need—a survey from Germany?
For the diagnosis, prevention and therapy of malnutrition, it is important to estimate the energy and fluid requirements of an individual patient. To our knowledge, it is unknown how accurately medical doctors...
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Article
Selection of optimal combinations of target genes for therapeutic multi-gene silencing based on miRNA co-regulation
Therapeutic gene silencing is a promising approach for treatment of cancer. Despite substantial efforts, however, only few such therapeutic methods have been clinically tested. The heterogeneity in gene expres...
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Article
Polarizabilities of SiN (N = 8–75) clusters from molecular beam electric deflection experiments
We have studied the polarizabilities of neutral silicon clusters with 8 to 75 atoms at 300 K employing the molecular beam deflection technique. In the range of 8 to 30 atoms the polarizability is strongly size...
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Article
Alexithymia and impaired facial affect recognition in multiple sclerosis
Despite the high relevance of emotion processing for social functioning, the study of the impairment of facial affect in multiple sclerosis (MS) has received little attention. Previous research reported eviden...
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Article
„Deep sequencing“ und prädiktive Modellierung als Konzept therapeutischer Entscheidungsfindungen in der Onkologie
Eine genaue Kenntnis der komplexen Aktivierungsmechanismen zellulärer Signalwege und deren molekulare Vernetzung sind für Planung und Prädiktion des Ansprechens zielgerichteter Therapien von großer Bedeutung. ...
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Article
Open AccessThe Filter Imager SuFI and the Image Stabilization and Light Distribution System ISLiD of the Sunrise Balloon-Borne Observatory: Instrument Description
We describe the design of the Sunrise Filter Imager (SuFI) and the Image Stabilization and Light Distribution (ISLiD) unit onboard the Sunrise balloon borne solar observatory. This contribution provides the neces...
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Article
Three-dimensional imaging of magnetic domains
Magnetic domains have been the subject of much scientific investigation since their theoretical existence was first postulated by P.-E. Weiss over a century ago. Up to now, the three-dimensional (3D) domain st...
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Article
Open AccessPSMB7 is associated with anthracycline resistance and is a prognostic biomarker in breast cancer
To date individual markers have failed to correctly predict resistance against anticancer agents in breast cancer. We used gene expression patterns attributable to chemotherapy-resistant cells to detect potent...
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Article
Survival, neuron-like differentiation and functionality of mesenchymal stem cells in neurotoxic environment: the critical role of erythropoietin
Mesenchymal stem cells (MSCs) can ameliorate symptoms in several neurodegenerative diseases. However, the toxic environment of a degenerating central nervous system (CNS) characterized by hypoxia, glutamate (G...
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Chapter and Conference Paper
Impact of the IDO2 blocker D-1-methyltryptophan on the IDO activity of human tumors and dendritic cells
Clinical phase-I-trials with cancer patients have been started with the aim of inducing tumor immunity by blocking the immunosuppressive action of indoleamine-2,3-dioxygenase (IDO) with the IDO2-inhibitor dextro-...
