108 Result(s)

Protocol

In Vivo Visualization and Quantification of Mitochondrial Morphology in C. elegans

Caenorhabditis elegans is a highly versatile model system, intensively used for functional, genetic, cytometric, and integrative studies. Due to its simplicity and large muscle cell number, C. elegans has frequen...

R. de Boer, R. L. Smith, W. H. De Vos, E. M. M. Manders… in Mitochondrial Medicine (2021)

Article

Impact of age, gender and CYP2C9/2C19 genotypes on dose-adjusted steady-state serum concentrations of valproic acid—a large-scale study based on naturalistic therapeutic drug monitoring data

Valproic acid (VPA) has an extensive interindividual pharmacokinetic variability. Published data regarding the impact of gender, age, and CYP2C9/2C19 genetics on VPA variability are conflicting, and the purpose o...

R. L. Smith, T. Haslemo, H. Refsum, E. Molden in European Journal of Clinical Pharmacology (2016)

Article

Statistical downscaling of precipitation on a spatially dependent network using a regional climate model

We present a detailed downscaling simulation methodology for generating precipitation events, conditioned on external climate covariates, on a network of meteorological stations. These events can be input to h...

R. J. Erhardt, L. E. Band, R. L. Smith… in Stochastic Environmental Research and Risk… (2015)

Article

Acute ‘limited’ magnetic resonance imaging in childhood stroke—an illustrative case

Paediatric stroke is a major cause of morbidity and death in children. There is often a delay in making the diagnosis because common differential diagnoses such as migraine and seizures need to be considered a...

C. I. Miteff, G. Subramanian, J. E. Brown, M. P. Wall, T. J. Alchin… in Emergency Radiology (2015)

Article

17 novel polymorphic microsatellite markers for the giant water bug, Abedus herberti (Belostomatidae)

The giant water bug (Abedus herberti) is a large flightless insect that is a keystone predator in aridland aquatic habitats. Extended droughts, possibly due to climate change and groundwater pum**, are causing ...

T. S. Daly-Engel, R. L. Smith, D. S. Finn… in Conservation Genetics Resources (2012)

Article

Differential recruitment of nuclear receptor coregulators in ligand-dependent transcriptional repression by estrogen receptor-α

Estrogen receptors (ERs) are normally expressed in breast tissues and mediate hormonal functions during development and in female reproductive physiology. In the majority of breast cancers, ERs are involved in...

K W Merrell, J D Crofts, R L Smith, J H Sin, K E Kmetzsch, A Merrell… in Oncogene (2011)

Article

Near-Infrared Emission from a Porous Silicon Device

Visible to near-infrared emission is produced from a porous silicon device under current injection. The porous silicon emitter is fabricated by selectively under-etching a p-n junction. The device is rectifyin...

J. Penczek, A. Knoesen, H. W. H. Lee, R. L. Smith in MRS Online Proceedings Library (2011)

Article

Microfluidic device for the combinatorial application and maintenance of dynamically imposed diffusional gradients

This article reports a microfluidic device for the generation of stable, steady-state, user-defined concentration profiles for the long-term maintenance of stable diffusion gradients. The microinstrument allow...

R. L. Smith, C. J. Demers, S. D. Collins in Microfluidics and Nanofluidics (2010)

Article

Denitrification Potential in Stream Sediments Impacted by Acid Mine Drainage: Effects of pH, Various Electron Donors, and Iron

Acid mine drainage (AMD) contaminates thousands of kilometers of stream in the western United States. At the same time, nitrogen loading to many mountain watersheds is increasing because of atmospheric deposit...

J. L. Baeseman, R. L. Smith, J. Silverstein in Microbial Ecology (2006)

Article

Assessment of Nitrification Potential in Ground Water Using Short Term, Single-Well Injection Experiments

Nitrification was measured within a sand and gravel aquifer on Cape Cod, MA, using a series of single-well injection tests. The aquifer contained a wastewater-derived contaminant plume, the core of which was a...

R. L. Smith, L. K. Baumgartner, D. N. Miller, D. A. Repert… in Microbial Ecology (2006)

Article

Adaptive inventory control models for supply chain management

Uncertainties inherent in customer demands make it difficult for supply chains to achieve just-in-time inventory replenishment, resulting in loosing sales opportunities or kee** excessive chain-wide inventor...

C.O. Kim, J. Jun, J.K. Baek, R.L. Smith… in The International Journal of Advanced Manu… (2005)

Article

Ocular toxoplasmosis: the role of retinal pigment epithelium migration in infection

Our aim was to study the migration of retinal pigmented epithelium (RPE) into the retinal layer during infection of C57BL/6 mice with Toxoplasma gondii. Eyes from infected and non-infected animals were analyzed o...

R. C. Tedesco, R. L. Smith, S. Corte-Real, K. S. Calabrese in Parasitology Research (2004)

Article

Trimethylamine and odorous sweat

Analysis of sweat collected from patients experiencing ichthyohidriosis, and from volunteers in whom this odour phenomenon had been artificially induced, showed that trimethylamine was the major causative factor.

S. C. Mitchell, R. L. Smith in Journal of Inherited Metabolic Disease (2003)

Article

Fatigue and proof testing of an aircraft auxiliary fuel tank

R. L. Smith, T. Farquhar, D. Arola, S. Bhonsale, D. Sullivan in Experimental Techniques (2002)

Article

Seed-specific, developmentally regulated genes of peanut

Four cDNAs of seed-specific and developmentally regulated peanut (Arachis hypogaea L.) genes were identified by differential screening of a peanut-seed cDNA library using cDNA probes constructed from mRNAs isolat...

O. G. Paik-Ro, J. C. Seib, R. L. Smith in Theoretical and Applied Genetics (2002)

Chapter and Conference Paper

Microneedle Array for Transdermal Bio-Fluid Sampling and Drug Delivery

This paper presents a microfabricated array of silicon microneedles, integrated with fluidic microchannels, designed for the extraction of extracellular fluid constituents from just beneath the skin. Biofluid ...

E. Mukerjee, S. D. Collins, R. L. Smith… in Micro Total Analysis Systems 2001 (2001)

Article

Effects of steam explosion processing and organic acids on CCA removal from treated wood waste

Chromated copper arsenate (CCA) is the primary wood preservative used in the United States. CCA products are used for decking, fencing, retaining walls, docks, poles, and highway sign posts. Since CCA became ...

R. J. Shiau, R. L. Smith, B. Avellar in Wood Science and Technology (2000)