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Article
Redesigning the FDMT Food Chain Transfer Model: Now Probabilistically Enabled and Fully Flexible
In Europe, the two main nuclear accident response decision support systems in use are ARGOS and JRODOS, both of which make use of the FDMT (Food Chain and Dose Module for Terrestrial pathways) model to simulat...
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Article
Open AccessCommunication of prostate cancer cells with bone cells via extracellular vesicle RNA; a potential mechanism of metastasis
The role of extracellular vesicles (EVs) as vehicles for cell-to-cell communication between a tumour and its environment is a relatively new concept. The hypothesis that EVs may be critical in co-opting tissue...
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Article
Acute ‘limited’ magnetic resonance imaging in childhood stroke—an illustrative case
Paediatric stroke is a major cause of morbidity and death in children. There is often a delay in making the diagnosis because common differential diagnoses such as migraine and seizures need to be considered a...
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Article
The Distribution of 137Cs, 90Sr, and 241Am in Waterbodies of Different Origins in the Belarusian Part of Chernobyl Exclusion Zone
The accident at the Chernobyl Nuclear Power Plant (ChNPP) resulted in the radioactive contamination of vast regions of Belarus including waterbodies of various types found within the watershed of the Pripyat R...
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Article
Expansion of tubenose gobies Proterorhinus semilunaris into western Lake Erie and potential effects on native species
The Eurasian freshwater tubenose goby Proterorhinus semilunaris (formerly Proterorhinus marmoratus) invaded the Laurentian Great Lakes in the 1990s, presumably via ballast water from transoceanic cargo ships. Tub...
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Article
Assessment of the reproductive capacity of Pinus sylvestris trees growing under conditions of chronic exposure to radionuclides of uranium and thorium series
The reproductive capacity of Scots pine (Pinus sylvestris L.) has been estimated in trees from the population growing in an area used to store tailings from uranium ore processing and radium production. Under suc...
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Article
A study of Hassawi rice (Oryza sativa L.) in terms of its carbohydrate hydrolysis (in vitro) and glycaemic and insulinaemic indices (in vivo)
A high prevalence of Type 2 diabetes exists in Saudi Arabia. Epidemiological evidence suggests that low glycaemic index (GI) diets reduce diabetes risk. Yet, little is known about the GI of traditional Saudi A...
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Article
Inter-comparison of models to estimate radionuclide activity concentrations in non-human biota
A number of models have recently been, or are currently being, developed to enable the assessment of radiation doses from ionising radiation to non-human species. A key component of these models is the ability...
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Article
Plasmodesmata transport of GFP alone or fused to potato virus X TGBp1 is diffusion driven
Plasmodesmata (Pd) provide a pathway for exchanging various macromolecules between neighboring plant cells. Researchers routinely characterize the mobility of the green-fluorescent protein (GFP) and GFP fusion...
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Article
The Use of Bone Markers in a 6-Week Study to Assess the Efficacy of Oral Clodronate in Patients with Metastatic Bone Disease
Biochemical markers of bone metabolism are strongly associated with skeletal complications in metastatic bone disease. The bisphosphonate clodronate reduces skeletal morbidity by inhibiting bone resorption. Th...
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Article
Open AccessHigh incidence of late effects found in Hodgkin's lymphoma survivors, following recall for breast cancer screening
Assessment of late effects in a cohort of female Hodgkin's lymphoma patients treated with mantle radiotherapy, identified from the DoH breast cancer screening recall showed high mortality and frequent undiagno...
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Article
Polysynaptic pathways from the vestibular nuclei to the lateral mammillary nucleus of the rat: substrates for vestibular input to head direction cells
The activity of some neurons in the lateral mammillary nucleus (LMN) of the rat corresponds with the animal’s current head direction (HD). HD cells have been studied extensively but the circuitry responsible f...
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Article
Open AccessBone resorption predicts for skeletal complications in metastatic bone disease
Relationships between the rate of bone resorption (measured by urinary N-telopeptide (Ntx) excretion) and a range of skeletal complications have been evaluated in patients with metastatic bone disease. A total...
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Article
Integration of soil solarization with chemical, biological and cultural control for the management of soilborne diseases of vegetables
The long-term effectiveness of soil solarization integrated with (integration of pest management [IPM]) a biological control agent (Trichoderma virens), chemical fungicide (pentachloronitrobenzene [PCNB]), organi...
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Article
Open AccessA novel strategy for NQO1 (NAD(P)H:quinone oxidoreductase, EC 1.6.99.2) mediated therapy of bladder cancer based on the pharmacological properties of EO9
The indolequinone EO9 demonstrated good preclinical activity but failed to show clinical efficacy against a range of tumours following intravenous drug administration. A significant factor in EO9's failure in ...
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Article
Linoleic acid metabolism in the spontaneously diabetic rat: Δ6-desaturase activity vs. product/precursor ratios
The activity of Δ6-desaturase of linoleic acid, a rate-limiting step in the formation of arachidonic acid, is decreased in animal models of severe, uncontrolled diabetes. The aim of the study was to measure th...
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Article
Open AccessPsychosocial predictors of outcome: time to relapse and survival in patients with early stage melanoma
This study explored psychosocial predictors of relapse and survival in early stage melanoma patients. Patients with locoregional melanoma whose tumour thickness exceeded 0.69 mm, seen at the Sydney Melanoma Un...
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Article
Patterns over time in quality of life, co** and psychological adjustment in late stage melanoma patients: An application of multilevel models
Background: Quality of life (QOL) assessment is an important component within cancer research. There is often variability in QOL scores both between patients and across time. Understanding this variability in te...
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Article
Reduced vas deferens contraction and male infertility in mice lacking P2X1 receptors
P2X1 receptors for ATP are ligand-gated cation channels, present on many excitable cells including vas deferens smooth muscle cells1,2,3,4,5. A substantial component of the contractile response of the vas deferen...
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Article
An evaluation of the diagnostic yield from bitewing radiographs of small approximal and occlusal carious lesions in a low prevalence sample in vitro using different film types and speeds
Aim: To compare diagnostic yield in caries diagnosis from D- and E-speed films.
