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  1. Article

    Open Access

    Author Correction: Rescue of germ cells in dnd crispant embryos opens the possibility to produce inherited sterility in Atlantic salmon

    An amendment to this paper has been published and can be accessed via a link at the top of the paper.

    Hilal Güralp, Kai O. Skaftnesmo, Erik Kjærner‑Semb, Anne Hege Straume in Scientific Reports (2021)

  2. Article

    Open Access

    Insulin-like 3 affects zebrafish spermatogenic cells directly and via Sertoli cells

    Pituitary hormones can use local signaling molecules to regulate target tissue functions. In adult zebrafish testes, follicle-stimulating hormone (Fsh) strongly increases the production of insulin-like 3 (Insl...

    Diego Crespo, Luiz H. C. Assis, Yu Ting Zhang, Diego Safian in Communications Biology (2021)

  3. Article

    Open Access

    Development of supermale and all-male Atlantic salmon to research the vgll3 allele - puberty link

    Farmed Atlantic salmon are one of the most economically significant global aquaculture products. Early sexual maturation of farmed males represents a significant challenge to this industry and has been linked ...

    Per Gunnar Fjelldal, Tom J. Hansen, Anna Wargelius, Fernando Ayllon in BMC Genetics (2020)

  4. Article

    Open Access

    Rescue of germ cells in dnd crispant embryos opens the possibility to produce inherited sterility in Atlantic salmon

    Genetic introgression of escaped farmed Atlantic salmon (Salmo salar) into wild populations is a major environmental concern for the salmon aquaculture industry. Using sterile fish in commercial aquaculture opera...

    Hilal Güralp, Kai O. Skaftnesmo, Erik Kjærner-Semb, Anne Hege Straume in Scientific Reports (2020)

  5. Article

    Open Access

    Correction to: Entry into puberty is reflected in changes in hormone production but not in testicular receptor expression in Atlantic salmon (Salmo salar)

    Following publication of the original article [1], the authors would like to apologize for an error in Fig. 5e, the correct graph is presented below and shows the significant increase in pituitary mRNA levels of

    Rüdiger W. Schulz, Geir Lasse Taranger in Reproductive Biology and Endocrinology (2019)

  6. Article

    Open Access

    Entry into puberty is reflected in changes in hormone production but not in testicular receptor expression in Atlantic salmon (Salmo salar)

    Puberty in male Atlantic salmon in aquaculture can start as early as after the first winter in seawater, stunts growth and entails welfare problems due to the maturation-associated loss of osmoregulation capac...

    Rüdiger W. Schulz, Geir Lasse Taranger in Reproductive Biology and Endocrinology (2019)

  7. Article

    Open Access

    The initiation of puberty in Atlantic salmon brings about large changes in testicular gene expression that are modulated by the energy status

    When puberty starts before males reach harvest size, animal welfare and sustainability issues occur in Atlantic salmon (Salmo salar) aquaculture. Hallmarks of male puberty are an increased proliferation activity ...

    Diego Crespo, Jan Bogerd, Elisabeth Sambroni, Florence LeGac, Eva Andersson in BMC Genomics (2019)

  8. Article

    Open Access

    Vgll3 and the Hippo pathway are regulated in Sertoli cells upon entry and during puberty in Atlantic salmon testis

    Vgll3 is linked to age at maturity in Atlantic salmon (Salmo salar). However, the molecular mechanisms involving Vgll3 in controlling timing of puberty as well as relevant tissue and cell types are currently unkn...

    Erik Kjærner-Semb, Fernando Ayllon, Lene Kleppe, Elin Sørhus in Scientific Reports (2018)

  9. Article

    Open Access

    Sex steroid production associated with puberty is absent in germ cell-free salmon

    In all vertebrates studied so far, germ cells are not required for pubertal maturation of the gonadal steroidogenic system, subsequent development of secondary sex characteristics and reproductive behavior. To...

    Lene Kleppe, Eva Andersson, Kai Ove Skaftnesmo, Rolf B. Edvardsen in Scientific Reports (2017)

  10. Article

    Open Access

    Dnd knockout ablates germ cells and demonstrates germ cell independent sex differentiation in Atlantic salmon

    Introgression of farmed salmon escapees into wild stocks is a major threat to the genetic integrity of wild populations. Using germ cell-free fish in aquaculture may mitigate this problem. Our study investigat...

    Anna Wargelius, Sven Leininger, Kai Ove Skaftnesmo, Lene Kleppe in Scientific Reports (2016)

  11. No Access

    Article

    Effect of in vivo chronic exposure to clotrimazole on zebrafish testis function

    Clotrimazole is an azole fungicide used as a human pharmaceutical that is known to inhibit cytochrome P450 (CYP) enzymatic activities, including several steroidogenic CYP. In a previous report, we showed that ...

    Damien Baudiffier, Nathalie Hinfray in Environmental Science and Pollution Resear… (2013)

  12. Article

    Open Access

    Sex differentiation in Atlantic cod (Gadus morhua L.): morphological and gene expression studies

    In differentiated gonochoristic species, a bipotential gonad develops into an ovary or testis during sex differentiation. Knowledge about this process is necessary to improve methods for masculinizing genetica...

    Trine Haugen, Fernanda FL Almeida, Eva Andersson in Reproductive Biology and Endocrinology (2012)

  13. Article

    Open Access

    Completion of meiosis in male zebrafish (Danio rerio) despite lack of DNA mismatch repair gene mlh1

    Mlh1 is a member of DNA mismatch repair (MMR) machinery and is also essential for the stabilization of crossovers during the first meiotic division. Recently, we have shown that zebrafish mlh1 mutant males are co...

    Marcelo C. Leal, Harma Feitsma, Edwin Cuppen, Luiz R. França in Cell and Tissue Research (2008)

  14. No Access

    Article

    Social stimulation, nuptial colouration, androgens and immunocompetence in a sexual dimorphic cichlid fish

    The nature of the costs maintaining honesty of sexual signalling in inter- and intrasexual interactions remains a contentious issue. For carotenoid-based colour ornaments, it has been hypothesized that the hon...

    Peter D. Dijkstra, Renske Hekman, Rüdiger W. Schulz in Behavioral Ecology and Sociobiology (2007)

  15. No Access

    Article

    Spermatogenesis and its endocrine regulation

    Three major phases compose spermatogenesis: mitotic proliferation of spermatogonia, meiosis of spermatocytes, and spermiogenesis, the restructuring of spermatids into flagellated spermatozoa. The process is fu...

    Rüdiger W. Schulz, Takeshi Miura in Fish Physiology and Biochemistry (2002)

  16. No Access

    Article

    Specific binding of 11-ketotestosterone in an androgen target organ, the kidney of the male three-spined stickleback,Gasterosteus aculeatus

    The kidney of male three-spined stickleback,Gasterosteus aculeatus, hypertrophies during the breeding season and produces a “glue” which is used in the building of the nest. This hypertrophy is androgen dependent...

    Staffan Jakobsson, Ian Mayer, Rüdiger W. Schulz in Fish Physiology and Biochemistry (1996)

  17. No Access

    Article

    Testicular responsiveness to gonadotropic hormonein vitro and Leydig and Sertoli cell ultrastructure during pubertal development of male African catfish (Clarias gariepinus)

    The gonadotropin (GTH)-stimulated testicular androgen secretionin vitro and the ultrastructure of Leydig and Sertoli cells was studied during the pubertal development in male African catfish. Testicular weight in...

    Rüdiger W. Schulz, Karlien Lubberink in Fish Physiology and Biochemistry (1996)