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Article
Open AccessCOVID-19 in the neighbourhood: the socio-spatial selectivity of severe COVID-19 cases in Sweden, March 2020–June 2021
In this paper we analyse spatial and temporal variation in the risk of intensive care unit (ICU) admission for COVID-19 in Sweden. The analysis is based on geocoded and time-stamped data from the Swedish Inten...
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Article
Open AccessIdentification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets
The virus life cycle depends on host-virus protein-protein interactions, which often involve a disordered protein region binding to a folded protein domain. Here, we used proteomic peptide phage display (ProP-...
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Article
Open AccessOccupational exposure to noise and dust in Swedish soft paper mills and mortality from ischemic heart disease and ischemic stroke: a cohort study
To elucidate whether occupational noise exposure increases the mortality from ischemic heart disease (IHD) and stroke, and if exposure to paper dust modified the risks.
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Article
Open AccessLarge-scale phage-based screening reveals extensive pan-viral mimicry of host short linear motifs
Viruses mimic host short linear motifs (SLiMs) to hijack and deregulate cellular functions. Studies of motif-mediated interactions therefore provide insight into virus-host dependencies, and reveal targets for...
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Article
Open AccessCancer incidence in a cohort of Swedish merchant seafarers between 1985 and 2011
Lung cancer, mesothelioma and several lifestyle-associated cancer forms have been reported more common in merchant seafarers. However, few studies reflect recent occupational settings and women seafarers are u...
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Article
Open AccessThe dynamic properties of a nuclear coactivator binding domain are evolutionarily conserved
Evolution of proteins is constrained by their structure and function. While there is a consensus that the plasticity of intrinsically disordered proteins relaxes the structural constraints on evolution there i...
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Article
Open AccessLarge scale discovery of coronavirus-host factor protein interaction motifs reveals SARS-CoV-2 specific mechanisms and vulnerabilities
Viral proteins make extensive use of short peptide interaction motifs to hijack cellular host factors. However, most current large-scale methods do not identify this important class of protein-protein interact...
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Open AccessCardiovascular mortality in a Swedish cohort of female industrial workers exposed to noise and shift work
The aim was to study mortality due to cardiovascular disease as well as total mortality, among female industrial workers, and the association to occupational noise and shift work.
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Article
Open AccessCorrection to: Physical exercise augmented cognitive behaviour therapy for older adults with generalised anxiety disorder (PEXACOG): study protocol for a randomized controlled trial
Following the publication of our article [1], we have become aware of one error in the exclusion criteria, inconsistencies in Figure 1 and Figure 2, and a typo in the reference list.
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Article
Open AccessMortality from cardiovascular disease in a cohort of Swedish seafarers
The aim of this study was to investigate whether Swedish seafarers have increased mortality from cardiovascular disease compared with the general population.
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Article
Open AccessCriterion validity of the Ekblom-Bak and the Åstrand submaximal test in an elderly population
The aim of this study was to validate the submaximal Ekblom-Bak test (EB-test) and the Åstrand test (Å-test) for an elderly population.
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Article
Open AccessTranscriptomic analysis of dead end knockout testis reveals germ cell and gonadal somatic factors in Atlantic salmon
Sustainability challenges are currently hampering an increase in salmon production. Using sterile salmon can solve problems with precocious puberty and genetic introgression from farmed escapees to wild popula...
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Open AccessLung function and paper dust exposure among workers in a soft tissue paper mill
To study respiratory effects of exposure to soft paper dust exposure, a relationship that is rarely studied.
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Article
Open AccessCorrection to: Entry into puberty is reflected in changes in hormone production but not in testicular receptor expression in Atlantic salmon (Salmo salar)
Following publication of the original article [1], the authors would like to apologize for an error in Fig. 5e, the correct graph is presented below and shows the significant increase in pituitary mRNA levels of
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Article
Open AccessEntry into puberty is reflected in changes in hormone production but not in testicular receptor expression in Atlantic salmon (Salmo salar)
Puberty in male Atlantic salmon in aquaculture can start as early as after the first winter in seawater, stunts growth and entails welfare problems due to the maturation-associated loss of osmoregulation capac...
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Article
Open AccessThe initiation of puberty in Atlantic salmon brings about large changes in testicular gene expression that are modulated by the energy status
When puberty starts before males reach harvest size, animal welfare and sustainability issues occur in Atlantic salmon (Salmo salar) aquaculture. Hallmarks of male puberty are an increased proliferation activity ...
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Article
Open AccessThe influence of vgll3 genotypes on sea age at maturity is altered in farmed mowi strain Atlantic salmon
In Atlantic salmon in the wild, age at maturity is strongly influenced by the vgll3 locus. Under farming conditions, light, temperature and feeding regimes are known significantly advance or delay age at maturity...
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Open AccessPhysical exercise augmented cognitive behaviour therapy for older adults with generalised anxiety disorder (PEXACOG): study protocol for a randomized controlled trial
Generalised anxiety disorder (GAD) is a frequent and severe anxiety disorder among older adults. GAD increases the risk of develo** other disorders such as depression and coronary heart disease. Older adults...
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Article
Open AccessCriterion validity and test-retest reliability of SED-GIH, a single item question for assessment of daily sitting time
Sedentary behaviour has been closely linked to metabolic and cardiovascular health and is therefore of importance in disease prevention. A user-friendly tool for assessment of sitting time is thus needed. Prev...
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Open AccessThe transition state structure for binding between TAZ1 of CBP and the disordered Hif-1α CAD
Intrinsically disordered proteins (IDPs) are common in eukaryotes. However, relatively few experimental studies have addressed the nature of the rate-limiting transition state for the coupled binding and foldi...