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Open AccessEvaluation of mandibular motion in adolescents with skeletal class II division 1 malocclusion during mandibular advancement using clear functional aligners: a prospective study
This study aimed to evaluate the characteristics of mandibular protrusive condylar trajectory in adolescents with skeletal Class II Division 1 malocclusion and the changes of condylar trajectory during mandibu...
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Article
Open AccessThree-dimensional spatial analysis of temporomandibular joint in adolescent Class II division 1 malocclusion patients: comparison of Twin-Block and clear functional aligner
Our study aimed to use three-dimensional (3D) spatial morphological measurement methods to compare the influence of Twin-Block and clear functional aligners on the temporomandibular joint (TMJ) of adolescent C...
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Article
Open AccessCapturing nascent extracellular vesicles by metabolic glycan labeling-assisted microfluidics
Extracellular vesicle (EV) secretion is a dynamic process crucial to cellular communication. Temporally sorting EVs, i.e., separating the newly-produced ones from the pre-existing, can allow not only deep unde...
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Article
Open AccessThree-dimensional spatial analysis of the temporomandibular joint in adult patients with Class II division 2 malocclusion before and after orthodontic treatment: a retrospective study
To investigate changes in the three-dimensional (3D) spatial morphology of the temporomandibular joint (TMJ) and condyle position in adult patients with Class II division 2 malocclusion using a 3D spatial meas...
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Open AccessNovel insight into the underlying dysregulation mechanisms of immune cell-to-cell communication by analyzing multitissue single-cell atlas of two COVID-19 patients
How does SARS-CoV-2 cause lung microenvironment disturbance and inflammatory storm is still obscure. We here performed the single-cell transcriptome sequencing from lung, blood, and bone marrow of two dead COV...
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Open AccessCharacteristics of lymphocyte subset alterations in COVID-19 patients with different levels of disease severity
Coronavirus disease 2019 (COVID-19) is a respiratory disorder caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which had rapidly spread all over the world and caused public health emerge...
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Article
Self-powered and broadband germanium/PEDOT:PSS heterojunction photodetectors for near-infrared biomedical imaging applications
To develop high-performance photodetectors (PDs) as near-infrared (NIR) imaging sensors, researchers have either proposed new photoelectric materials, introduced complicated interface-processing steps, or crea...
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Article
Open AccessEfficacy and Safety of Tocilizumab Treatment COVID-19 Patients: A Case-Control Study and Meta-Analysis
As the pandemic progresses, the pathophysiology of COVID-19 is becoming more apparent, and the potential for tocilizumab is increasing. However, the clinical efficacy and safety of tocilizumab in the treatment...
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Article
Study on the Properties of Novel Soft Magnetic Composites of FeSiAl
In this paper, we compounded the FeSiAl powder with a novel amorphous inorganic insulation agent (AIIA). Silicone resin (3 wt.%) was used as organic insulating agent, and the inorganic insulating agent was Fe83.5
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Article
Effect of Cu on microstructure, magnetic properties of antiperovskite nitrides CuxNFe4−x
For soft magnetic materials, especially new intermetallic compounds, some good soft magnetic properties, such as high permeability, low power loss, as well as superior DC-bias properties, will determine their ...
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Article
Optimal average annual mean surface air temperature for East Asia since 1901
In this paper, the authors use Climate Research Unit (CRU) land surface air temperature (SAT) and empirical orthogonal function (EOF)-based spectral optimal averaging (SOA) method to estimate the regional aver...
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Article
Preparation and Characterization of NdFeB/PrCo5 Nanocomposite Magnetic Materials
We first developed NdFeB/PrCo5 nanocomposite magnetic material by high-energy ball milling, and the influence of the different contents of PrCo5 on the magnetic properties of NdFeB was studied by means of XRD, DS...
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Article
Open AccessThe susceptibility of FSHB -211G > T and FSHR G-29A, 919A > G, 2039A > G polymorphisms to men infertility: an association study and meta-analysis
Male infertility is a complex disorder caused by genetic, developmental, endocrine, or environmental factors as well as unknown etiology. Polymorphisms in the follicle stimulating hormone beta subunit (FSHB) (rs1...
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Article
Trends and uncertainties in surface air temperature over the Tibetan Plateau, 1951–2013
Trends and uncertainties of surface air temperature over the Tibetan Plateau (TP) are evaluated by using observations at 100 meteorological stations during the period 1951–2013. The sampling error variances of...
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Article
Iriflophenone Glycosides from Aquilaria sinensis
Five iriflophenone glycosides were obtained from the stems of Aquilaria sinensis by phytochemical methods. Their structures were determined by spectroscopic methods and comparison with literature data. As a no...
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Article
Open AccessHyperhomocysteinaemia in rats is associated with erectile dysfunction by impairing endothelial nitric oxide synthase activity
To investigate the effect of hyperhomocysteinaemia (HHCy) on penile erectile function in a rat model, a methionine-rich diet was used in which erectile function, the reproductive system, and nitric oxide synth...
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Article
Open AccessPrenatal diagnosis and genetic counseling in a fetus associated with risk of Angelman syndrome with a small supernumerary marker chromosome derived from chromosome 22
Angelman syndrome (AS) is a neurodevelopmental disorder. AS patients concomitant with sSMC are rather rare events. It will provide more useful and proper information for genetic counseling to identify the sSMC...
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Article
Open AccessPolymorphisms in Protamine 1 and Protamine 2 predict the risk of male infertility: a meta-analysis
Several studies have investigated the association between polymorphisms in protamine 1 and 2 genes and male infertility risk, with inconsistent results to date. This meta-analysis based on the 13 published cas...
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Article
Forsythin inhibits lipopolysaccharide-induced inflammation by suppressing JAK-STAT and p38 MAPK signalings and ROS production
Forsythin (FOR) is an active ingredient extracted from the fruit of the medicinal plant Forsythia suspensa (Thunb.) Vahl. Here, we investigated the effect of FOR on LPS-induced inflammatory response and the under...