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Article
Open AccessOrganic-inorganic hybrid piezotronic bipolar junction transistor for pressure sensing
With the rapid development of the Internet of Things (IoTs), wearable sensors are playing an increasingly important role in daily monitoring of personal health and wellness. The signal-to-noise-ratio has becom...
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Article
Measurement and Control of Residual Stress of High-Grade and Large-Diameter Welded Pipe for Oil and Gas Transportation
It was discussed that the research progress and technical achievements had been obtained in the field of residual stress measurement and control of high-grade and large-diameter welded pipe for oil and gas tra...
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Article
Simulation study of intra-beam scattering effect in the HALF storage ring with Piwinski model
The Hefei Advanced Light Facility (HALF) will be a VUV and soft X-ray diffraction-limited storage ring (DLSR), and its high density of electron bunches makes the intra-beam scattering (IBS) effect very serious.
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Article
Open AccessMacrophages communicate with mesangial cells through the CXCL12/DPP4 axis in lupus nephritis pathogenesis
Lupus nephritis (LN) occurs in 50% of cases of systemic lupus erythematosus (SLE) and is one of the most serious complications that can occur during lupus progression. Mesangial cells (MCs) are intrinsic cells...
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Article
Smart cities dynamic performance assessment in China using vertical and horizontal deviation maximization method and driving indicator analysis
With the development of information technology, such as cloud computing and 5G technologies, the construction of smart cities has been an essential part of the city’s long-term development strategy for the 14t...
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Article
Sustainability evaluation based on the three-stage difference-driven model: a case study of the province, autonomous region, and municipality in Western China
Sustainability is a key factor in regional economic, social, and environmental development. In this study, we constructed a regional sustainability system of 24 indicators by combining the Sustainable Developm...
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Article
Numerical model establishment and experimental study of milling head cooling water flow rate
The thermal error suppression rate depends on the cooling effect of the water cooling system, and the cooling water flow rate is a direct factor affecting the cooling effect. To better reduce the thermal error...
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Article
Open AccessIntegrated Analysis of Chromatin and Transcriptomic Profiling Identifies PU.1 as a Core Regulatory Factor in Microglial Activation Induced by Chronic Cerebral Hypoperfusion
In addition to causing white matter lesions, chronic cerebral hypoperfusion (CCH) can also cause damage to gray matter, but the underlying molecular mechanisms remain largely unknown. In order to obtain a bett...
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Article
Study on parameters of T-type cooling system for motorized spindle based on thermal characteristics
Thermal errors, due to temperature rise, account for about two-thirds of the machining error of the motorized spindle. Cooling is an important means of improving the temperature properties of motorized spindle...
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Article
In vitro and in vivo metabolic activation and hepatotoxicity of chlorzoxazone mediated by CYP3A
Chlorzoxazone (CZX), a benzoxazolone derivative, has been approved for the treatment of musculoskeletal disorders to relieve localized muscle spasm. However, its idiosyncratic toxicity reported in patients bro...
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Article
Open AccessPiezo1 channel exaggerates ferroptosis of nucleus pulposus cells by mediating mechanical stress-induced iron influx
To date, several molecules have been found to facilitate iron influx, while the types of iron influx channels remain to be elucidated. Here, Piezo1 channel was identified as a key iron transporter in response ...
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Article
Open AccessGenetic fusion of CCL11 to antigens enhances antigenicity in nucleic acid vaccines and eradicates tumor mass through optimizing T-cell response
Nucleic acid vaccines have shown promising potency and efficacy for cancer treatment with robust and specific T-cell responses. Improving the immunogenicity of delivered antigens helps to extend therapeutic ef...
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Article
Open AccessRemodeling the tumor-immune microenvironment by anti-CTLA4 blockade enhanced subsequent anti-PD-1 efficacy in advanced nasopharyngeal carcinoma
Sequential immunotherapy has shown certain advantages in malignancy. Here, we aim to evaluate the efficacy of sequential anti-CTLA-4 and anti-PD-1 treatment for recurrent or metastatic nasopharyngeal carcinoma...
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Article
Superior Latent Heat Eutectic Salt Na2CO3-Li2CO3-LiF for Thermal Energy Storage: Preparation and Performance Investigation
In this paper, a novel ternary eutectic salt Na2CO3-Li2CO3-LiF was designed and investigated for concentrated solar power (CSP). The FactSage software was used to predict the composition and eutectic point of Na2
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Article
Keypoint-based contextual representations for hand pose estimation
Most current methods for the hand pose estimation ignore the pixel-level relationship of hand keypoints, e.g. four specific keypoints in the same finger can form a semantically continuous area at pixel level. ...
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Article
Urban sustainability assessment based on sentiment analysis and entropy weight method: case study in Liaoning, China
Sustainability is indispensable for cities to achieve long-term positive development. This paper evaluated the sustainability of 14 cities in Liaoning province from 2015 to 2019. A new weighting method was pro...
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Article
A Family of Aggregation Operators for Group Decision-Making from the Perspective of Incentive Management
Aggregating various decision information provided by a group of decision makers (DMs) into an integrated one is essential for seeking the optimal solution. This paper aims to propose an effective method for in...
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Article
Open AccessPrevalence and dissemination of mcr-9.1-producing non-typhoidal Salmonella strains from diarrhea patients throughout China during 2010–2020
The emergence of mobilized colistin resistance (mcr) genes has raised significant concerns as they pose a public health issue. The prevalence of mcr genes, particularly the newly discovered mcr-9 gene, in non-typ...
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Article
The effects of scarcity mindset on envy: the mediating role of the sense of control
This study explored the relationship between scarcity mindset and envy and the possible mediating mechanisms. We induced participants’ scarcity mindset. Individuals with a scarcity mindset experienced more env...
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Article
Open AccessCortistatin prevents glucocorticoid-associated osteonecrosis of the femoral head via the GHSR1a/Akt pathway
Long-term use of glucocorticoids (GCs) is known to be a predominant cause of osteonecrosis of the femoral head (ONFH). Moreover, GCs can mediate apoptosis of various cell types by exaggerating oxidative stress...
