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    Article

    Berbamine Hydrochloride inhibits lysosomal acidification by activating Nox2 to potentiate chemotherapy-induced apoptosis via the ROS-MAPK pathway in human lung carcinoma cells

    Autophagy is typically activated in cancer cells as a rescue strategy in response to cellular stress (e.g., chemotherapy). Herein, we found that Berbamine Hydrochloride (Ber) can act as an effective inhibitor ...

    Yujuan Zhan, Qiugu Chen, Yue Song, **anli Wei, Tingxiu Zhao in Cell Biology and Toxicology (2023)

  2. Article

    Open Access

    Identification of Fangjihuangqi Decoction as a late-stage autophagy inhibitor with an adjuvant anti-tumor effect against non-small cell lung cancer

    Clinically, although chemotherapy is one of the most commonly used methods of treating tumors, chemotherapeutic drugs can induce autophagic flux and increase tumor cell resistance, leading to drug tolerance. T...

    Qiugu Chen, Yuan Liao, Yujiao Liu, Yue Song, Junbo Jiang, Zhen zhang in Chinese Medicine (2023)

  3. Article

    Open Access

    Integrated analysis reveals the pivotal interactions between immune cells in the melanoma tumor microenvironment

    Melanoma is the most lethal type of skin cancer. Despite the breakthroughs in the clinical treatment of melanoma using tumor immunotherapy, many patients do not benefit from these immunotherapies because of mu...

    Jiawei Chen, Shan Hu, Huiqi Wang, Tingxiu Zhao, Yue Song in Scientific Reports (2022)

  4. Chapter and Conference Paper

    Effects of Key Size, Gap and the Location of Key Characters on the Usability of Touchscreen Devices in Input Tasks

    Touchscreen technology has gained increasing popularity over the last decade in a variety of personal, public and occupational settings. It is of great significance to investigate the effects of interface desi...

    Da Tao, Qiugu Chen, Juan Yuan, Shuang Liu in Engineering Psychology and Cognitive Ergon… (2017)