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Open AccessImplantation initiation of self-assembled embryo-like structures generated using three types of mouse blastocyst-derived stem cells
Spatially ordered embryo-like structures self-assembled from blastocyst-derived stem cells can be generated to mimic embryogenesis in vitro. However, the assembly system and developmental potential of such str...
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Article
Open AccessLong non-coding RNAs involved in the regulatory network during porcine pre-implantation embryonic development and iPSC induction
Long non-coding RNAs (lncRNA) play a key role in the orchestration of transcriptional regulation during development and many other cellular processes. The importance of the regulatory co-expression network was...
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Article
Open AccessDouble knockout of Bax and Bak from kidney proximal tubules reduces unilateral urethral obstruction associated apoptosis and renal interstitial fibrosis
Interstitial fibrosis, a common pathological feature of chronic kidney diseases, is often associated with apoptosis in renal tissues. To determine the associated apoptotic pathway and its role in renal interst...
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Article
Open AccessInduction of Germ Cell-like Cells from Porcine Induced Pluripotent Stem Cells
The ability to generate germ cells from pluripotent stem cells (PSCs) is valuable for human regenerative medicine and animal breeding. Germ cell-like cells (GCLCs) have been differentiated from mouse and human...
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Article
Open AccessImprovement in Mouse iPSC Induction by Rab32 Reveals the Importance of Lipid Metabolism during Reprogramming
Induced pluripotent stem cells (iPSCs) have variable expression levels of a series of genes that affect their pluripotent potential, but the regulatory mechanisms controlling reprogramming remain unclear. By t...
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Article
Imaging bacteriorhodopsinlike molecules of claretmembranes from Tibet halobacteria xz515 by atomic force microscope
HalobacteriaH.sp.xz 515 was isolated from a salt lake in Tibet. Although proton release-and-uptake across claret membrane is in reverse order compared to bacteriorhodopsin in purple membrane fromHalobacterium Sal...