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  1. Article

    Open Access

    Implantation initiation of self-assembled embryo-like structures generated using three types of mouse blastocyst-derived stem cells

    Spatially ordered embryo-like structures self-assembled from blastocyst-derived stem cells can be generated to mimic embryogenesis in vitro. However, the assembly system and developmental potential of such str...

    Shaopeng Zhang, Tianzhi Chen, Naixin Chen, Dengfeng Gao in Nature Communications (2019)

  2. Article

    Open Access

    Long non-coding RNAs involved in the regulatory network during porcine pre-implantation embryonic development and iPSC induction

    Long non-coding RNAs (lncRNA) play a key role in the orchestration of transcriptional regulation during development and many other cellular processes. The importance of the regulatory co-expression network was...

    Liang Zhong, Haiyuan Mu, Bingqiang Wen, Wei Zhang, Qingqing Wei in Scientific Reports (2018)

  3. Article

    Open Access

    Double knockout of Bax and Bak from kidney proximal tubules reduces unilateral urethral obstruction associated apoptosis and renal interstitial fibrosis

    Interstitial fibrosis, a common pathological feature of chronic kidney diseases, is often associated with apoptosis in renal tissues. To determine the associated apoptotic pathway and its role in renal interst...

    Shuqin Mei, Lin Li, Qingqing Wei, Jielu Hao, Yunchao Su, Changlin Mei in Scientific Reports (2017)

  4. Article

    Open Access

    Induction of Germ Cell-like Cells from Porcine Induced Pluripotent Stem Cells

    The ability to generate germ cells from pluripotent stem cells (PSCs) is valuable for human regenerative medicine and animal breeding. Germ cell-like cells (GCLCs) have been differentiated from mouse and human...

    Hanning Wang, **zhu **ang, Wei Zhang, Junhong Li, Qingqing Wei in Scientific Reports (2016)

  5. Article

    Open Access

    Improvement in Mouse iPSC Induction by Rab32 Reveals the Importance of Lipid Metabolism during Reprogramming

    Induced pluripotent stem cells (iPSCs) have variable expression levels of a series of genes that affect their pluripotent potential, but the regulatory mechanisms controlling reprogramming remain unclear. By t...

    Yangli Pei, Liang Yue, Wei Zhang, Yanliang Wang, Bingqiang Wen in Scientific Reports (2015)

  6. No Access

    Article

    Imaging bacteriorhodopsinlike molecules of claretmembranes from Tibet halobacteria xz515 by atomic force microscope

    HalobacteriaH.sp.xz 515 was isolated from a salt lake in Tibet. Although proton release-and-uptake across claret membrane is in reverse order compared to bacteriorhodopsin in purple membrane fromHalobacterium Sal...

    Lin Tang, Qing’an Sun, Qingguo Li, Yibo Huang, Qingqing Wei in Chinese Science Bulletin (2001)