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Article
Open AccessDevelopmental stage-specific A-to-I editing pattern in the postnatal pineal gland of pigs (Sus scrofa)
RNA editing is a widespread post-transcriptional modification mechanism in mammalian genomes. Although many editing sites have been identified in domestic pigs (Sus scrofa), little is known about the characterist...
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Article
Open AccessPluripotent stem cells secrete Activin A to improve their epiblast competency after injection into recipient embryos
It is not fully clear why there is a higher contribution of pluripotent stem cells (PSCs) to the chimera produced by injection of PSCs into 4-cell or 8-cell stage embryos compared with blastocyst injection. He...
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Article
Open AccessImprovement in Mouse iPSC Induction by Rab32 Reveals the Importance of Lipid Metabolism during Reprogramming
Induced pluripotent stem cells (iPSCs) have variable expression levels of a series of genes that affect their pluripotent potential, but the regulatory mechanisms controlling reprogramming remain unclear. By t...
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Article
Open AccessSpecific gene-regulation networks during the pre-implantation development of the pig embryo as revealed by deep sequencing
Because few studies exist to describe the unique molecular network regulation behind pig pre-implantation embryonic development (PED), genetic engineering in the pig embryo is limited. Also, this lack of resea...
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Article
Overcoming barriers to the clinical utilization of iPSCs: reprogramming efficiency, safety and quality
Differentiated cells can be reprogrammed into pluripotent stem cells, known as “induced pluripotent stem cells” (iPSCs), through the overexpression of defined transcription factors. The creation of iPSC lines ...
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Article
Effects of chronic heat stress on the expressions of heat shock proteins 60, 70, 90, A2, and HSC70 in the rabbit testis
Few studies have focused on the expression of heat shock proteins (HSPs) after chronic heat stress. The objective of this study was to investigate the effect of chronic high temperature–humidity index treatmen...
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Article
Developmental expression of heat shock proteins 60, 70, 90, and A2 in rabbit testis
Currently, no reports exist concerning the expression patterns and developmental changes of heat shock proteins (HSPs) in the reproductive system of the male rabbit. In the present study, the testes of rabbits...
