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Article
Open AccessActivated phosphoinositide 3-kinase δ syndrome caused by PIK3CD mutations: expanding the phenotype
Germline heterozygous gain-of-function (GOF) mutations in the PIK3CD gene lead to a rare primary immunodeficiency disease known as activated phosphoinositide 3-kinase (PI3K) δ syndrome type 1(APDS1). Affected pat...
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Article
Clinical features of CNOT3-associated neurodevelopmental disorder in three Chinese patients
CNOT3 is the central component of the CCR4-NOT protein complex, which is a global regulator of RNA polymerase II transcription. Loss of function mutations in CNOT3 lead to intellectual developmental disorder with...
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Chapter and Conference Paper
MoCoSR: Respiratory Motion Correction and Super-Resolution for 3D Abdominal MRI
Abdominal MRI is critical for diagnosing a wide variety of diseases. However, due to respiratory motion and other organ motions, it is challenging to obtain motion-free and isotropic MRI for clinical diagnosis...
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Chapter and Conference Paper
Robust Segmentation via Topology Violation Detection and Feature Synthesis
Despite recent progress of deep learning-based medical image segmentation techniques, fully automatic results often fail to meet clinically acceptable accuracy, especially when topological constraints should b...
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Chapter and Conference Paper
Mesh-Based 3D Motion Tracking in Cardiac MRI Using Deep Learning
3D motion estimation from cine cardiac magnetic resonance (CMR) images is important for the assessment of cardiac function and diagnosis of cardiovascular diseases. Most of the previous methods focus on estima...
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Article
Open AccessBig data security access control algorithm based on memory index acceleration in WSNs
The access control is used to ensure these data security when WSN (wireless sensor network) with a large number of base stations transmits huge amount of data to a data center server. Meanwhile big data system...
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Chapter and Conference Paper
Unsupervised Cross-domain Image Classification by Distance Metric Guided Feature Alignment
Learning deep neural networks that are generalizable across different domains remains a challenge due to the problem of domain shift. Unsupervised domain adaptation is a promising avenue which transfers knowle...
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Chapter and Conference Paper
Automated Detection of Congenital Heart Disease in Fetal Ultrasound Screening
Prenatal screening with ultrasound can lower neonatal mortality significantly for selected cardiac abnormalities. However, the need for human expertise, coupled with the high volume of screening cases, limits ...
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Chapter and Conference Paper
Ultrasound Video Summarization Using Deep Reinforcement Learning
Video is an essential imaging modality for diagnostics, e.g. in ultrasound imaging, for endoscopy, or movement assessment. However, video hasn’t received a lot of attention in the medical image analysis commun...
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Article
Highly Soluble Phenylethynyl-terminated Imide Oligomers and Thermosetting Polyimides Based on 2,2′,3,3′-Biphenyltetracarboxylic Dianhydride
The properties of a series of imide oligomers were characterized according to their molecular weights, solubility, and thermal and rheological properties. This series of imide oligomers was synthesized via a two-...
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Chapter and Conference Paper
Representation Disentanglement for Multi-task Learning with Application to Fetal Ultrasound
One of the biggest challenges for deep learning algorithms in medical image analysis is the indiscriminate mixing of image properties, e.g. artifacts and anatomy. These entangled image properties lead to a seman...
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Chapter and Conference Paper
Semi-supervised Learning of Fetal Anatomy from Ultrasound
Semi-supervised learning methods have achieved excellent performance on standard benchmark datasets using very few labelled images. Anatomy classification in fetal 2D ultrasound is an ideal problem setting to...
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Chapter and Conference Paper
Automatic Shadow Detection in 2D Ultrasound Images
Automatically detecting acoustic shadows is of great importance for automatic 2D ultrasound analysis ranging from anatomy segmentation to landmark detection. However, variation in shape and similarity in inten...
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Article
Open AccessHuman settlement and regional development in the context of climate change: a spatial analysis of low elevation coastal zones in China
Low elevation coastal zone (LECZ) in China is densely populated and economically developed, which is exposed to increasing risks of hazards related to climate change and sea level rise. To mitigate risks and a...
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Article
Yeast-Incorporated Gallium Attenuates Glucocorticoid-Induced Bone Loss in Rats by Inhibition of Bone Resorption
Glucocorticoids (GC) are potent anti-inflammatory agents and widely used for the treatment of many immune-mediated and inflammatory diseases, whereas GC-induced osteoporosis (GIOP) is the most common cause of ...
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Chapter and Conference Paper
Spectral Unmixing for Hyperspectral Image Classification with an Adaptive Endmember Selection
Hyperspectral classification techniques are widely used for detailed analysis of the earth surface. However, mixed pixels caused by the relatively low spatial resolution of the imaging system are the big burde...
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Article
Genome-wide association study in Han Chinese identifies four new susceptibility loci for coronary artery disease
Dongfeng Gu and colleagues report a genome-wide association study for coronary artery disease in Han Chinese individuals. They identify four loci newly associated with coronary artery disease.
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Article
Ginkgo biloba extract enhances glucose tolerance in hyperinsulinism-induced hepatic cells
Ginkgo biloba, an herbal medication, is capable of lowering glucose, fat, and lipid peroxide in diabetic patients. In the current study, we tested the hypothesis that Ginkgo biloba extract (GBE) prevented hyperin...
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Article
An excellent ablative composite based on PBO reinforced EPDM
Short poly(p-phenylene-2,6-benzobisoxazole) (PBO) fibers were first used to reinforce ethylene–propylene–diene terpolymer (EPDM) as thermal insulation materials. The effects of PBO fiber length and content on the...
