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Article
Open AccessArtificial intelligence-based prognostic model accurately predicts the survival of patients with diffuse large B-cell lymphomas: analysis of a large cohort in China
Diffuse large B-cell lymphomas (DLBCLs) display high molecular heterogeneity, but the International Prognostic Index (IPI) considers only clinical indicators and has not been updated to include molecular data....
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Article
Open AccessAssociation of serum CTRP4 levels with vascular endothelial function in patients with type 2 diabetes mellitus: CTRP4 ameliorating inflammation, proliferation and migration in human umbilical vein endothelial cells
We investigated the correlation between serum C1q/TNF-related protein 4 (CTRP4) level and flow-mediated dilation (FMD) in patients with type 2 diabetes mellitus (T2DM), and evaluated the biological effects of ...
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Chapter and Conference Paper
A Simple Method for Studying Aero-Propulsion Characteristics of a Distributed Electric Propulsion Aircraft
Distributed electric propulsion (DEP) is a popular research area in the aerospace field, with most research focusing on investigating the aerodynamic features of DEP configurations through numerical simulations.
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Article
T1-weighted images-based radiomics for structural lesions evaluation in patients with suspected axial spondyloarthritis
The aim of this study was to investigate the feasibility of radiomics based on T1-weighted images (T1WI) for assessing sacroiliac joint (SIJ) structural lesions in patients with suspected axial spondyloarthrit...
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Article
Berberine inhibits gluconeogenesis in spontaneous diabetic rats by regulating the AKT/MAPK/NO/cGMP/PKG signaling pathway
This work was aimed to investigate the action mechanism of berberine (BBR) on gluconeogenesis. The effects of BBR were examined in rat primary hepatocytes and confirmed in vivo in spontaneous diabetic rats. Pr...
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Article
Can radiomics replace the SPARCC scoring system in evaluating bone marrow edema of sacroiliac joints in patients with axial spondyloarthritis?
To develop an objective and efficient method based on radiomics to evaluate bone marrow edema (BMO) of sacroiliac joints (SIJs) by magnetic resonance imaging (MRI) in patients with axial spondyloarthritis (axS...
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Article
Open AccessDeciphering and advancing CAR T-cell therapy with single-cell sequencing technologies
Chimeric antigen receptor (CAR) T-cell therapy has made remarkable progress in cancer immunotherapy, but several challenges with unclear mechanisms hinder its wide clinical application. Single-cell sequencing ...
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Article
Clinical features of CNOT3-associated neurodevelopmental disorder in three Chinese patients
CNOT3 is the central component of the CCR4-NOT protein complex, which is a global regulator of RNA polymerase II transcription. Loss of function mutations in CNOT3 lead to intellectual developmental disorder with...
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Article
Open AccessThe average 30-minute post-prandial C-peptide predicted diabetic retinopathy progress: a retro-prospective study
The conclusion between Connecting peptide (C-peptide) and diabetic chronic complication was controversial. The purpose of this study is to explore the possible association between average C-peptide with diabet...
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Article
Dissolved Organic Matter Features in Black Soldier Fly Larvae Frass Derived From Two Types of Meat and Bone Meals with Straw Amendments
Bioconversion of meat and bone meal (MBM), a kind of organic waste, by black soldier fly larvae (BSFL) is promising. Knowledge on the dissolved organic matter (DOM) features in larval frass is important for th...
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Article
Open AccessPeripheral immune cell profiling of double-hit lymphoma by mass cytometry
Double-hit or Triple-hit lymphoma (DHL/THL) is a subset of high-grade B cell lymphoma harboring rearrangements of MYC and BCL2 and/or BCL6, and usually associate with aggressive profile, while current therapies t...
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Article
Open AccessDynamic response characteristics and damage rule of graphite ore rock under different strain rates
In the process of mining graphite mine, rock mass is often subjected to dynamic loads such as blasting or mechanical crushing, which involves dynamic responses of different strain rates, and blasting and crush...
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Article
Quantum classifiers for domain adaptation
Transfer learning (TL), a crucial subfield of machine learning, aims to accomplish a task in the target domain with the acquired knowledge of the source domain. Specifically, effective domain adaptation (DA) f...
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Article
Correction to: TPTEP1 suppresses high glucose‑induced dysfunction in retinal vascular endothelial cells by interacting with STAT3 and targeting VEGFA
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Chapter and Conference Paper
Anomaly Detection with Ensemble Empirical Mode Decomposition for Secure QUIC Communications: A Simple Use Case
QUIC (Quick UDP Internet Connections) proposed by Google is a new secure general-purpose network transport protocol. Compared with TCP and TLS, QUIC combines the advantages of many other protocols and is a new...
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Chapter and Conference Paper
Residual Inter-slice Feature Learning for 3D Organ Segmentation
Although a large number of 2D convolutional neural networks have been reported and used for medical image segmentation, most of them still face the following two problems. First, these networks employ 2D convo...
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Article
Clinical safety study of photobiomodulation in acute spinal cord injury by scattering fiber
The study aimed to design a reliable and straightforward PBM method by implanting a medical scattering fiber above surgically exposed spinal cord in SCI patients. Moreover, the safety of this method was examin...
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Article
Open AccessRisk Factors for Generalization in Patients with Ocular Myasthenia Gravis: A Multicenter Retrospective Cohort Study
Many patients with ocular myasthenia gravis (OMG) progress to generalized disease within the first 2 years of the onset of ocular symptoms. Several retrospective studies have identified risk factors associated...
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Article
Open AccessHigh efficacy of PD-1 inhibitor after initial failure of PD-L1 inhibitor in Relapsed/Refractory classical Hodgkin Lymphoma
We sought to understand the clinical course and molecular phenotype of patients who showed disease progression after programmed cell death ligand 1 (PD-L1) inhibitor treatment but subsequently responded to PD-...
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Chapter and Conference Paper
A Multi-modal System for Video Semantic Understanding
This paper proposes a video semantic understanding system based on multi-modal data fusion. The system includes two sub-models, the video classification tag model (VCT) and the video semantic tag model (VST), ...
