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Article
Identification and introgression of a novel leaf rust resistance gene from Thinopyrum intermedium chromosome 7Js into wheat
A novel leaf rust resistance locus located on a terminal segment (0–69.29 Mb) of Thinopyrum intermedium chromosome arm 7JsS has been introduced into wheat genome for disease resistance breeding.
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Article
Molecular characterization of stable QTL and putative candidate genes for grain zinc and iron concentrations in two related wheat populations
Major QTL for grain zinc and iron concentrations were identified on the long arm of chromosomes 2D and 6D. Gene-based KASP markers were developed for putative candidate genes TaIPK1-2D and TaNAS10-6D.
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Article
Establishment and identification of six wheat-Thinopyrum ponticum disomic addition lines derived from partial amphiploid **aoyan 7430
Six wheat-Thinopyrum ponticum disomic addition lines derived from partial amphiploid **aoyan 7430 were identified using in situ hybridization and SNP microarray, the homoeologous group and stripe rust resistance ...
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Article
Open AccessDeficiency of PPP6C protects TNF-induced necroptosis through activation of TAK1
Necroptotic cell death is mediated by a super-molecular complex called necrosome which consists of receptor-interacting protein kinase 1 and 3 (RIPK1, RIPK3) and mixed-lineage kinase domain-like protein (MLKL)...
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Article
Cytogenetic identification and molecular marker development of a novel wheat–Thinopyrum ponticum translocation line with powdery mildew resistance
A new wheat–Thinopyrum ponticum translocation line with excellent powdery mildew resistance was produced, and alien-specific PCR markers and FISH probes were developed by SLAF-seq.
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Article
Map** QTL for seedling morphological and physiological traits under normal and salt treatments in a RIL wheat population
The genetic basis of 27 seedling traits under normal and salt treatments was fully analyzed in a RIL wheat population, and seven QTL intervals were validated in two other genetic populations.
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Article
Chromosomal composition analysis and molecular marker development for the novel Ug99-resistant wheat–Thinopyrum ponticum translocation line WTT34
A novel Ug99-resistant wheat–Thinopyrum ponticum translocation line was produced, its chromosomal composition was analyzed and specific markers were developed.
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Article
Map** QTL for agronomic traits under two levels of salt stress in a new constructed RIL wheat population
QTL for 15 agronomic traits under two levels of salt stress in dry salinity field were mapped in a new constructed RIL population utilizing a Wheat55K SNP array. Furthermore, eight QTL were validated in a coll...
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Article
Development and molecular cytogenetic identification of a new wheat-rye 4R chromosome disomic addition line with resistances to powdery mildew, stripe rust and sharp eyespot
A wheat-rye 4R chromosome disomic addition line with resistances to powdery mildew, stripe rust, sharp eyespot and high kernel number per spike was developed and characterized by molecular cytogenetic method a...
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Article
Physical map** of the blue-grained gene from Thinopyrum ponticum chromosome 4Ag and development of blue-grain-related molecular markers and a FISH probe based on SLAF-seq technology
A Thinopyrum ponticum chromosome 4Ag physical map was constructed, the blue-grained gene was localized, and related specific markers and a FISH probe were developed by SLAF-seq.
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Article
Multiple loci not only Rf3 involved in the restoration ability of pollen fertility, anther exsertion and pollen shedding to S type cytoplasmic male sterile in maize
Thirty loci for fertility restoration of pollen fertility, anther exsertion and pollen shedding to maize CMS-S were identified by GWAS.
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Article
In vivo and in vitro evaluation of effects of Mg-6Zn alloy on apoptosis of common bile duct epithelial cell
Biodegradable magnesium alloy implants have attracted much attention because of their excellent biocompatibility and good mechanical properties. However, effects of Mg alloy on cell apoptosis remain unclear. T...
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Article
Identification of combining ability loci for five yield-related traits in maize using a set of testcrosses with introgression lines
Combining ability is essential for hybrid breeding in crops. However, the genetic basis of combining ability remains unclear and has been seldom investigated. Identifying molecular markers associated with this...
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Article
Identification of amino acids involved in catalytic process of M. tuberculosis GlmU acetyltransferase
M. tuberculosis GlmU is a bifunctional enzyme with acetyltransferase activity in C-terminus and uridyltransferase activity in N-terminus, and it is involved in the biosynthesis of glycosyl donor ...
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Article
Mili and Miwi target RNA repertoire reveals piRNA biogenesis and function of Miwi in spermiogenesis
Piwi proteins bind a class of small germline RNAs, called piRNAs, whose biogenesis and functions are largely unknown. High-throughput sequencing after cross-linking and immunoprecipitation (HITS-CLIP) analysis...
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Article
Important roles of the conserved linker-KKS in human neuronal growth inhibitory factor
Metallothinein-3 (MT3), also named neuronal growth inhibitory factor (GIF), is attractive by its distinct neuronal growth inhibitory activity, which is not shared by other MT isoforms. The polypeptide chain of...
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Article
Effect of α-domain substitution on the structure, property and function of human neuronal growth inhibitory factor
Human metallothionein-3 (hMT3), also named human neuronal growth inhibitory factor (hGIF), is attractive due to its distinct neuronal growth inhibitory activity, which is not shown by other human MT isoforms. ...
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Article
The role of Thr5 in human neuron growth inhibitory factor
GIF, a member of the metallothionein (MT) family (assigned as MT3), is a neuron growth inhibitory factor that inhibits neuron outgrowth in Alzheimer’s disease. The conserved Thr5 is one of the main differences...