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  1. Article

    Open Access

    Exploring the Relationship Between Atorvastatin and Memory Loss: A Comprehensive Analysis Integrating Real-World Pharmacovigilance and Mendelian Randomization

    Atorvastatin is a drug widely used to prevent cardiovascular and cerebrovascular diseases. Current observational studies suggest that atorvastatin may be associated with cognitive dysfunction (especially memor...

    Kaiqin Chen, Yongtai Chen, Hesen Huang in Drugs in R&D (2024)

  2. Article

    Open Access

    Correction: Impact of non-pharmaceutical interventions during COVID-19 on future influenza trends in Mainland China

    **aofan Liu, Ying Peng, Zhe Chen, Fangfang Jiang, Fang Ni in BMC Infectious Diseases (2024)

  3. Article

    Open Access

    Application of root cause analysis and TEAMSTEPPS post intravesical gas explosion during transurethral resection of the prostate: a rare case report

    An intravesical gas explosion is a rare complication of transurethral resection of the prostate (TURP). It was first reported in English literature in 1926, and up to 2022 were only forty-one cases. Injury fro...

    I-Hung Chen, Cher-Min Fong, Hsing-Hua Stella Chang, Ying-Jui Ni in BMC Urology (2024)

  4. No Access

    Article

    Common and rare variants in genetic susceptibility analysis of mature B-cell neoplasm subtypes by whole exome sequencing

    Junwei Lin, Maoting Shen, Wenjuan **ao, Yuxin Chen, Shihui Yu, Yuhuan Meng in Leukemia (2024)

  5. Article

    Open Access

    Prevalence and disease burden of chronic cough in nine cities of China: an observational study

    Chronic cough (CC) is common in the general population of China, creating a difficult-to-ignore public health burden. However, there is a lack of research on the nationwide prevalence and disease burden of CC ...

    Lin Chen, Kim S.J. Lao, Fang Yi, Kai **a, Kefang Lai in BMC Pulmonary Medicine (2024)

  6. No Access

    Article

    Sodium Houttuyfonate Ameliorates DSS-induced Colitis Aggravated by Candida albicans through Dectin-1/NF-κB/miR-32-5p/NFKBIZ Axis Based on Intestinal microRNA Profiling

    Our previous research indicated that Sodium houttuyfonate (SH) can effectively ameliorate dextran sulfate sodium (DSS)-induced colitis exacerbated by Candida albicans. However, the underlying protective mechanism...

    Chen Xu, Liu Yang, Ting Cheng, Zixu Wang, Chengcheng Liu, **g Shao in Inflammation (2024)

  7. Article

    Open Access

    Constructing diagnostic signature of serum microRNAs using machine learning for early pan-cancer detection

    Cancer is a major public health concern and the second leading cause of death worldwide. Various studies have reported the use of serum microRNAs (miRNAs) as non-invasive biomarkers for cancer detection. Howev...

    Yuyan Xu, Wei Liao, Huanwei Chen, Mingxin Pan in Discover Oncology (2024)

  8. Article

    Open Access

    PCLAF induces bone marrow adipocyte senescence and contributes to skeletal aging

    Bone marrow adipocytes (BMAds) affect bone homeostasis, but the mechanism remains unclear. Here, we showed that exercise inhibited PCNA clamp-associated factor (PCLAF) secretion from the bone marrow macrophage...

    Lingqi **e, Yalun Cheng, Biao Hu, **n Chen, Yuze An, in Bone Research (2024)

  9. Article

    Open Access

    The association between systemic inflammation markers and paroxysmal atrial fibrillation

    Systemic inflammation markers have recently been identified as being associated with cardiac disorders. However, limited research has been conducted to estimate the pre-diagnostic associations between these ma...

    Xuechen Zhao, Lei Huang, Jianan Hu, Nake **, Jun Hong in BMC Cardiovascular Disorders (2024)

  10. Article

    Open Access

    The efficacy and safety of combined therapy with endobronchial tamponade and bronchial artery embolization for massive hemoptysis

    Massive hemoptysis is characterized by its life-threatening nature, potentially leading to airway obstruction and asphyxia. The objective of this study was to evaluate the clinical effectiveness of combining e...

    Chaohui Lin, Yanfeng Chen, Donglu Cai, Zhiyu Chen, Zhuli Peng in BMC Pulmonary Medicine (2024)

  11. Article

    Correction to: Successful Immune Reconstitution in a Patient with a TYK2 Deficiency after Allogeneic Stem Cell Transplantation from Unrelated Donors

    Yelei Gao, Ya Wang, Lina Zhou, Ge Lv, Jie Yu in Journal of Clinical Immunology (2024)

  12. No Access

    Article

    Immune checkpoint inhibitors-induced diabetes mellitus (review)

    Immune checkpoint inhibitors (ICIs) have become extensively utilized in the early-stage treatment of various cancers, offering additional therapeutic possibilities for patients with advanced cancer. However, c...

    Jiayi Chen, **aochen Hou, Yang Yang, Chenxi Wang, Jie Zhou, **gge Miao in Endocrine (2024)

  13. Article

    Open Access

    Progressive encephalomyelitis with rigidity and myoclonus: a pediatric case report and literature review

    Progressive encephalomyelitis with rigidity and myoclonus (PERM) is a rare and life-threatening autoimmune disease of the central nervous system. So far, only ten cases of PERM have been reported in children w...

    Yu Li, **g-wen Wang, Qi-hui Chen, Ruo-hao Wu, **ang-yang Luo in BMC Pediatrics (2024)

  14. Article

    Open Access

    Prognostic value of oxidative phosphorylation-related genes in hepatocellular carcinoma

    Hepatocellular carcinoma (HCC) is the most prevalent malignancies worldwide. Recently, oxidative phosphorylation (OXPHOS) has received extensive concern as an emerging target in antitumor therapy. However, the...

    Luzheng Liu, Jiacheng Chen, Fei Ye, Fengran Chu, Chaoluan Rao in Discover Oncology (2024)

  15. Article

    Open Access

    Vertebral bone quality score was associated with paraspinal muscles fat infiltration, but not modic classification in patients with chronic low back pain: a prospective cross-sectional study

    The lumbar vertebra and paraspinal muscles play an important role in maintaining the stability of the lumbar spine. Therefore, the aim of this study was to investigate the relationship between paraspinal muscl...

    Jiaxin Chen, Yilong Huang, Yingjuan Yang, Zhongwei Wang in BMC Musculoskeletal Disorders (2024)

  16. Article

    Open Access

    Impact of antiphospholipid antibodies on cardiac valve lesions in systemic lupus erythematosus: a systematic review and meta-analysis

    This meta-analysis assesses antiphospholipid antibodies’ (aPLs) impact on heart valve disease in Systemic Lupus Erythematosus (SLE) patients. We searched PubMed, Embase, Cochrane, and Web of Science up to Janu...

    Siyun Chen, Yangzhong Zhou, Chuhan Wang, Hui Jiang in Clinical and Experimental Medicine (2024)

  17. Article

    Open Access

    Detectability of intracranial vessel wall atherosclerosis using black-blood spectral CT: a phantom and clinical study

    Computed tomography (CT) is the usual modality for diagnosing stroke, but conventional CT angiography reconstructions have limitations.

    Fan Zhang, Hui Yao, Eran Langzam, Qinglin Meng in European Radiology Experimental (2024)

  18. Article

    Open Access

    Associations amongst dynamic knee stiffness during gait, quadriceps stiffness, and the incidence of knee osteoarthritis over 24 months: a cohort study with a mediation analysis

    Decreased strength and increased stiffness of the quadriceps have been associated with a higher risk of develo** knee osteoarthritis (OA) in elders. Dynamic joint stiffness (DJS) represents collective resist...

    Zongpan Li, Kam-Lun Leung, Chen Huang, ** Huang in BMC Musculoskeletal Disorders (2024)

  19. Article

    Open Access

    Clinical Outcomes in Patients with CKD and Rapid or Non-rapid eGFR Decline: A Report from the DISCOVER CKD Retrospective Cohort

    This analysis examined the baseline characteristics and clinical outcomes of patients with chronic kidney disease (CKD) and rapid or non-rapid estimated glomerular filtration rate (eGFR) decline, using retrosp...

    Hiddo Heerspink, Stephen Nolan, Juan-Jesus Carrero, Matthew Arnold in Advances in Therapy (2024)

  20. Article

    Open Access

    Targeting S100A12 to Improve Angiogenesis and Accelerate Diabetic Wound Healing

    Long-term inflammation and impaired angiogenesis are thought to be the causes of delayed healing or nonhealing of diabetic wounds. S100A12 is an essential pro-inflammatory factor involved in inflammatory react...

    Shitian Qin, Fan Bie, Shuying Chen, Yingbin Xu, Lei Chen, Bin Shu, Fan Yang in Inflammation (2024)

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