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Article
An analytical solution to predict slip-buckling failure of bedding rock slopes under the influence of top loading and earthquakes: Case studies of Hejia landslide and Tangjiashan landslide
Slip-buckling failure is a common occurrence in bedding rock slopes, and it can be triggered by long-term gravitational stress, earthquakes, top loading and intense rainfall. In this paper, an analytical solut...
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Article
Open AccessDe novo design of a nanoregulator for the dynamic restoration of ovarian tissue in cryopreservation and transplantation
The cryopreservation and transplantation of ovarian tissue underscore its paramount importance in safeguarding reproductive capacity and ameliorating reproductive disorders. However, challenges persist in ovar...
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Article
Clinical Value of the Quantitative Flow Ratio to Predict Long-term Target Vessel Failure in Patients with In-stent Restenosis after Drug-coated Balloon Angioplasty
The study sought to investigate the clinical predictive value of quantitative flow ratio (QFR) for the long-term target vessel failure (TVF) outcome in patients with in-stent restenosis (ISR) by using drug-coa...
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Article
Face Stability Assessment for Karst Tunnelling across a Filling-type Karst Cave
An innovative approach is introduced to ensure tunnel construction safety and determine the minimum safety thickness under filled-type karst cave conditions. Firstly, a computational model is developed with th...
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Article
Open AccessWnt/β-catenin signaling is a therapeutic target in anaplastic thyroid carcinoma
Anaplastic thyroid carcinoma (ATC) is a highly aggressive malignancy that has consistently shown Wnt/β-catenin (canonical) signaling activation in various study populations. There are currently no targetable t...
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Article
Open AccessPrecise and automated lung cancer cell classification using deep neural network with multiscale features and model distillation
Lung diseases globally impose a significant pathological burden and mortality rate, particularly the differential diagnosis between adenocarcinoma, squamous cell carcinoma, and small cell lung carcinoma, which...
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Article
Open AccessEfficacy and safety of intrapleural perfusion with hyperthermic chemotherapy for malignant pleural effusion: a meta-analysis
To evaluate the efficacy and safety of intrapleural perfusion with hyperthermic chemotherapy (IPHC) in treating malignant pleural effusion (MPE).
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Article
Characterization of whole genomes from recently emerging Mpox cases in several regions of China, 2023
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Article
Open AccessStructural insights into the functional mechanism of the ubiquitin ligase E6AP
E6AP dysfunction is associated with Angelman syndrome and Autism spectrum disorder. Additionally, the host E6AP is hijacked by the high-risk HPV E6 to aberrantly ubiquitinate the tumor suppressor p53, which is...
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Article
Open AccessMetabolic profiling identifies Qrich2 as a novel glutamine sensor that regulates microtubule glutamylation and mitochondrial function in mouse sperm
In our prior investigation, we discerned loss-of-function variants within the gene encoding glutamine-rich protein 2 (QRICH2) in two consanguineous families, leading to various morphological abnormalities in s...
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Article
Open AccessAssessing the clinical diagnostic value of anti-Müllerian hormone in polycystic ovarian syndrome and its correlation with clinical and metabolism indicators
This study investigated the association between Anti-Müllerian Hormone (AMH) and relevant metabolic parameters and assessed its predictive value in the clinical diagnosis of polycystic ovarian syndrome (PCOS).
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Article
Open AccessSystematic analyses of the factors influencing sperm quality in patients with SARS-CoV-2 infection
To figure out how does SARS-CoV-2 affect sperm parameters and what influencing factors affect the recovery of sperm quality after infection? We conducted a prospective cohort study and initially included 122 m...
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Article
Approaching the theoretical capacity of TiO2 anode in a photo-rechargeable lithium-ion battery
New generation of lithium-ion batteries (LIBs) integrating solar energy conversion and storage is emerging, as they could solve the fluctuation problem in the utilization of solar energy. Photo-rechargeable li...
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Article
A comparison of two PPP-RTK models: S-basis choice, network product precision, and user positioning performance
PPP-RTK combines the advantages of both precise point positioning (PPP) and real-time kinematic (RTK) techniques. While constructing PPP-RTK models based on undifferenced and uncombined observations offers app...
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Article
Optimizing ZWD estimation strategies for enhanced PPP-RTK performance
Precise Point Positioning-Real Time Kinematic (PPP-RTK), a synthesis of PPP and RTK techniques, is a highly precise positioning technique that has been extensively studied in the GNSS community. The Zenith Wet...
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Article
Open AccessAn acetate electrolyte for enhanced pseudocapacitve capacity in aqueous ammonium ion batteries
Ammonium ion batteries are promising for energy storage with the merits of low cost, inherent security, environmental friendliness, and excellent electrochemical properties. Unfortunately, the lack of anode ma...
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Article
Dynamic Effect of Landslides Triggered by Earthquake: A Case Study in Moxi Town of Luding County, China
The dynamic effect is a very important issue widely debated by scholars when studying the genetic and disaster-causing mechanisms of earthquake-triggered landslides. First, the dynamic effect mechanism and phe...
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Article
Open AccessAnalysis of the differentially expressed genes in the combs and testes of Qingyuan partridge roosters at different developmental stages
The sexual maturity of chickens is an important economic trait, and the breeding of precocious and delayed puberty roosters is an important selection strategy for broilers. The comb serves as an important seco...
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Article
Open AccessDelayed coastal inundations caused by ocean dynamics post-Hurricane Matthew
Post Hurricane Abnormal Water Level (PHAWL) poses a persistent inundation threat to coastal communities, yet unresolved knowledge gaps exist regarding its spatiotemporal impacts and causal mechanisms. Using a ...
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Article
Open AccessMic19 depletion impairs endoplasmic reticulum-mitochondrial contacts and mitochondrial lipid metabolism and triggers liver disease
Endoplasmic reticulum (ER)-mitochondria contacts are critical for the regulation of lipid transport, synthesis, and metabolism. However, the molecular mechanism and physiological function of endoplasmic reticu...
