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  1. Article

    Open Access

    Control of false discoveries in grouped hypothesis testing for eQTL data

    Expression quantitative trait locus (eQTL) analysis aims to detect the genetic variants that influence the expression of one or more genes. Gene-level eQTL testing forms a natural grouped-hypothesis testing st...

    Pratyaydipta Rudra, Yi-Hui Zhou, Andrew Nobel, Fred A. Wright in BMC Bioinformatics (2024)

  2. Article

    Open Access

    Model based heritability scores for high-throughput sequencing data

    Heritability of a phenotypic or molecular trait measures the proportion of variance that is attributable to genotypic variance. It is an important concept in breeding and genetics. Few methods are available fo...

    Pratyaydipta Rudra, W. Jenny Shi, Brian Vestal, Pamela H. Russell in BMC Bioinformatics (2017)