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Article
Association of serum levels of phenylalanine and tyrosine with hip fractures and frailty in older adults: The cardiovascular health study
This study examined if the amino acids phenylalanine or tyrosine contribute to risk of hip fracture or frailty in older adults. We determined that neither phenylalanine nor tyrosine are important predictors of...
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Article
Association of Immune Cell Subsets with Incident Hip Fracture: The Cardiovascular Health Study
In this study, we aimed to evaluate the association of innate and adaptive immune cell subsets in peripheral blood mononuclear cells (PBMCs) with hip fracture. To conduct this study, we used data from the Card...
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Article
The Association of Aromatic Amino Acids with Incident Hip Fracture, aBMD, and Body Composition from the Cardiovascular Health Study
In 5187 persons from the Cardiovascular Health Study, there was no significant association of dietary intakes of aromatic amino acids (AAA) with areal BMD of the hip or body composition. However, those who had...
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Article
Correction to: Transethnic insight into the genetics of glycaemic traits: fine-map** results from the Population Architecture using Genomics and Epidemiology (PAGE) consortium
The authors regret that Yinchang Lu’s name incorrectly included a middle initial in the author list. The details given in this erratum are correct.
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Article
Open AccessTransethnic insight into the genetics of glycaemic traits: fine-map** results from the Population Architecture using Genomics and Epidemiology (PAGE) consortium
Elevated levels of fasting glucose and fasting insulin in non-diabetic individuals are markers of dysregulation of glucose metabolism and are strong risk factors for type 2 diabetes. Genome-wide association st...
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Article
Association of Plasma SDF-1 with Bone Mineral Density, Body Composition, and Hip Fractures in Older Adults: The Cardiovascular Health Study
Aging is associated with an increase in circulating inflammatory factors. One, the cytokine stromal cell-derived factor 1 (SDF-1 or CXCL12), is critical to stem cell mobilization, migration, and homing as well...
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Reference Work Entry In depth
Hip Fracture Risk Is Strongly Related to Circulating Levels of the Advanced Glycation End Product Carboxy-Methyl Lysine (CML)
Advanced glycation end products (AGEs) are markers of oxidative stress, the process whereby the body is unable to neutralize the effects of oxygen radicals generated during the process of metabolism. Oxidative...
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Living Reference Work Entry In depth
Hip Fracture Risk Is Strongly Related to Circulating Levels of the Advanced Glycation End Product Carboxy-Methyl Lysine (CML)
Advanced glycation end products (AGEs) are markers of oxidative stress, the process whereby the body is unable to neutralize the effects of oxygen radicals generated during the process of metabolism. Oxidative...
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Article
No evidence of interaction between known lipid-associated genetic variants and smoking in the multi-ethnic PAGE population
Genome-wide association studies (GWAS) have identified many variants that influence high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, and/or triglycerides. However, environmental modif...
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Article
Open AccessGenetic variants associated with fasting glucose and insulin concentrations in an ethnically diverse population: results from the Population Architecture using Genomics and Epidemiology (PAGE) study
Multiple genome-wide association studies (GWAS) within European populations have implicated common genetic variants associated with insulin and glucose concentrations. In contrast, few studies have been conduc...
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Article
Open AccessInvestigation of gene-by-sex interactions for lipid traits in diverse populations from the population architecture using genomics and epidemiology study
High-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), and triglyceride (TG) levels are influenced by both genes and the environment. Genome-wide association studies (GWAS) ...
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Article
Open AccessEffects of smoking on the genetic risk of obesity: the population architecture using genomics and epidemiology study
Although smoking behavior is known to affect body mass index (BMI), the potential for smoking to influence genetic associations with BMI is largely unexplored.
