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Article
Association of serum levels of phenylalanine and tyrosine with hip fractures and frailty in older adults: The cardiovascular health study
This study examined if the amino acids phenylalanine or tyrosine contribute to risk of hip fracture or frailty in older adults. We determined that neither phenylalanine nor tyrosine are important predictors of...
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Article
Open AccessA plasma protein-based risk score to predict hip fractures
As there are effective treatments to reduce hip fractures, identification of patients at high risk of hip fracture is important to inform efficient intervention strategies. To obtain a new tool for hip fractur...
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Article
Association of Immune Cell Subsets with Incident Hip Fracture: The Cardiovascular Health Study
In this study, we aimed to evaluate the association of innate and adaptive immune cell subsets in peripheral blood mononuclear cells (PBMCs) with hip fracture. To conduct this study, we used data from the Card...
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Article
The associations of markers of endothelial dysfunction with hip fracture risk
Endothelial dysfunction underlies the development of atherosclerotic vascular disease, which in turn is associated with osteoporotic fractures. Here, we examined the association of two markers of endothelial d...
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Article
Open AccessDietary inflammatory index and cardiovascular disease risk in Hispanic women from the Women’s Health Initiative
To evaluate the association between the dietary inflammatory index (DII®) and incident cardiovascular disease (CVD) in Hispanic women from the Women’s Health Initiative (WHI), and to determine if body mass index ...
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Article
Cardiovascular autonomic nervous system function and hip fracture risk: the Cardiovascular Health Study
Among 1299 older adults with 24-h Holter monitoring data at baseline, followed for approximately 15 years, 190 incident hip fractures occurred. Increased heart rate variability was independently associated wit...
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Article
The Association of Aromatic Amino Acids with Incident Hip Fracture, aBMD, and Body Composition from the Cardiovascular Health Study
In 5187 persons from the Cardiovascular Health Study, there was no significant association of dietary intakes of aromatic amino acids (AAA) with areal BMD of the hip or body composition. However, those who had...
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Open AccessErratum: Large meta-analysis of genome-wide association studies identifies five loci for lean body mass
A correction to this article has been published and is linked from the HTML version of this article.
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Article
Open AccessLarge meta-analysis of genome-wide association studies identifies five loci for lean body mass
Lean body mass, consisting mostly of skeletal muscle, is important for healthy aging. We performed a genome-wide association study for whole body (20 cohorts of European ancestry with n = 38,292) and appendicular...
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Article
Association of Plasma SDF-1 with Bone Mineral Density, Body Composition, and Hip Fractures in Older Adults: The Cardiovascular Health Study
Aging is associated with an increase in circulating inflammatory factors. One, the cytokine stromal cell-derived factor 1 (SDF-1 or CXCL12), is critical to stem cell mobilization, migration, and homing as well...
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Article
Commentary: Death certificate reporting needs to be fixed
Something is wrong with the death reporting when there is a fivefold difference in the reported rates of fall mortality between Alabama and Vermont, two states in the United States. The problem is not unique h...
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Carbon cycling in Lake Erie during cultural eutrophication over the last century inferred from the stable carbon isotope composition of sediments
A ~106-cm sediment core from the eastern basin of Lake Erie was examined to investigate biogeochemical processes in this large lake during its cultural eutrophication over the last century. We measured stable ...
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Article
Records of nutrient-enhanced coastal ocean productivity in sediments from the Louisiana continental shelf
Shelf sediments from near the mouth of the Mississippi River were collected and analyzed to examine whether records of the consequences of anthropogenic nutrient loading are preserved. Cores representing appro...
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Article
Sedimentation rates, residence times and radionuclide inventories in Lake Baikal from 137Cs and 210Pb in sediment cores
RADIONUCLIDES in lake sediments may act as indicators of the sedimentation rate of particles on which they are adsorbed; these rates in turn provide a direct indication of the residence times of particles in t...
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Significance of Sediment Resuspension and Particle Settling
Seasonal particle characteristics and sediment-trap-measured resuspension rates are examined for the Laurentian Great Lakes and compared with other large, deep lakes. Results are used to estimate the influence...