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Article
Silent synapses dictate cocaine memory destabilization and reconsolidation
Cocaine-associated memories are persistent, but, on retrieval, become temporarily destabilized and vulnerable to disruptions, followed by reconsolidation. To explore the synaptic underpinnings for these memory...
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Article
Cocaine-Induced Synaptic Alterations in Thalamus to Nucleus Accumbens Projection
Exposure to cocaine induces addiction-associated behaviors partially through remodeling neurocircuits in the nucleus accumbens (NAc). The paraventricular nucleus of thalamus (PVT), which projects to the NAc mo...
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Article
Maturation of silent synapses in amygdala-accumbens projection contributes to incubation of cocaine craving
In rats self-administering cocaine, drug seeking behavior induced by a cocaine-paired cue increases progressively during cocaine withdrawal. The authors detected silent synapses in basolateral amygdala–to–nucl...
