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Open AccessGenes associated with cognitive ability and HAR show overlap** expression patterns in human cortical neuron types
GWAS have identified numerous genes associated with human cognition but their cell type expression profiles in the human brain are unknown. These genes overlap with human accelerated regions (HARs) implicated ...
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Article
Humoral and cellular response to the COVID-19 vaccine in immunocompromised children
A suboptimal response to the 2-dose COVID-19 vaccine series in the immunocompromised population prompted recommendations for a 3rd primary dose. We aimed to determine the humoral and cellular immune response t...
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Open AccessAuthor Correction: Human neocortical expansion involves glutamatergic neuron diversification
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Open AccessHuman neocortical expansion involves glutamatergic neuron diversification
The neocortex is disproportionately expanded in human compared with mouse1,2, both in its total volume relative to subcortical structures and in the proportion occupied by supragranular layers composed of neurons...
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Article
Correction to: Adverse drug reaction causality assessment tools for drug-induced Stevens-Johnson syndrome and toxic epidermal necrolysis: room for improvement
The correct name of the 9th Author is David J. Margolis. The original article was corrected.
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Article
Adverse drug reaction causality assessment tools for drug-induced Stevens-Johnson syndrome and toxic epidermal necrolysis: room for improvement
Establishment of causality between drug exposure and adverse drug reactions (ADR) is challenging even for serious ADRs such as Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN). Several causality a...
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Article
GLP-1 acts on habenular avoidance circuits to control nicotine intake
Nicotine has rewarding effects that motivate its consumption. In addition to these rewarding effects, nicotine also has aversive properties that motivate its avoidance. Here the authors identify a pathway in t...
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Article
Open AccessClinical Impact of an Antibiotic Stewardship Program at a Children’s Hospital
Antibiotic stewardship programs (ASP) improve appropriate antibiotic use. Data are limited on the clinical benefit of ASPs in children’s hospitals. This study’s objective was to determine the impact of an ASP ...
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Article
Maturation of silent synapses in amygdala-accumbens projection contributes to incubation of cocaine craving
In rats self-administering cocaine, drug seeking behavior induced by a cocaine-paired cue increases progressively during cocaine withdrawal. The authors detected silent synapses in basolateral amygdala–to–nucl...
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Effects of a behavioral intervention to reduce serodiscordant unsafe sex among HIV positive men who have sex with men: the Positive Connections randomized controlled trial study
Few behavioral interventions have been conducted to reduce high-risk sexual behavior among HIV-positive Men who have Sex with Men (HIV+ MSM). Hence, we lack well-proven interventions for this population. Posit...