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Article
Open AccessInvestigating phase separation properties of chromatin-associated proteins using gradient elution of 1,6-hexanediol
Chromatin-associated phase separation proteins establish various biomolecular condensates via liquid–liquid phase separation (LLPS), which regulates vital biological processes spatially and temporally. However...
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Article
Open AccessCurrent status of hand-foot-and-mouth disease
Hand-foot-and-mouth disease (HFMD) is a viral illness commonly seen in young children under 5 years of age, characterized by typical manifestations such as oral herpes and rashes on the hands and feet. These s...
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Article
Open AccessIGF2BP2-induced circRUNX1 facilitates the growth and metastasis of esophageal squamous cell carcinoma through miR-449b-5p/FOXP3 axis
Esophageal squamous cell carcinoma (ESCC) is one of the most common digestive malignancies with relatively high morbidity and mortality. Emerging evidence suggests circular RNAs (circRNAs) play critical roles ...
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Article
Design, synthesis and biological evaluation of isoxazole-containing biphenyl derivatives as small-molecule inhibitors targeting the programmed cell death-1/ programmed cell death-ligand 1 immune checkpoint
Monoclonal antibodies targeting the programmed cell death-1/ programmed cell death-ligand 1 (PD-1/PD-L1) immune checkpoint have achieved enormous success in cancer immunotherapy. But the antibody-based immunot...
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Article
Open AccessThe incubation period of COVID-19: a global meta-analysis of 53 studies and a Chinese observation study of 11 545 patients
The incubation period is a crucial index of epidemiology in understanding the spread of the emerging Coronavirus disease 2019 (COVID-19). In this study, we aimed to describe the incubation period of COVID-19 g...
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Article
Detection of ULF electromagnetic emissions as a precursor to two earthquakes in China
The geomagnetic data recorded by Kashi and **ghai observatories in China were analyzed with improved polarization method. We compared the result around 0.01 Hz which is thought to be useful to detect the ULF ...
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Article
Statistical study on great geomagnetic storms during solar cycle 23
Characteristics of great geomagnetic storms during solar cycle 23 were statistically investigated. Firstly, we focused on the uniqueness of solar cycle 23 by analyzing both the great storm number and sunspot n...
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Article
Synthesis and characterization of Ba0.5Sr0.5Co0.8Fe0.2O3−σ
Perovskite-type Ba0.5Sr0.5Co0.8Fe0.2O3−δ (BSCFO) powders were synthesized using two methods, solid-state reaction (SSR) method and citrate-EDTA complexing method (CC-EDTA). Then the powde...
