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Article
Robust principal component analysis based on tensor train rank and Schatten p-norm
For a given data, robust principal component analysis (RPCA) aims to exactly recover the low-rank and sparse components from it. To date, as the convex relaxations of tensor rank, a number of tensor nuclear no...
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Article
Open AccessIntrauterine phenotype features of fetuses with 7q11.23 microduplication syndrome
To share our experience on prenatal diagnosis of 7q11.23 microduplication syndrome and to further delineate the fetal phenotypes of the syndrome.
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Article
Open AccessInfantile fibrosarcoma of the perineum with dorsal metastasis in a neonate: a case report original
Infantile fibrosarcoma is a rare pediatric soft tissue tumor and usually appears in children before one year of age. Distal extremities constitute the most frequently affected locations, and other tissues such...
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Article
Open AccessThe incubation period of COVID-19: a global meta-analysis of 53 studies and a Chinese observation study of 11 545 patients
The incubation period is a crucial index of epidemiology in understanding the spread of the emerging Coronavirus disease 2019 (COVID-19). In this study, we aimed to describe the incubation period of COVID-19 g...
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Chapter
Kidney Diseases
The kidneys are two bean-shaped organs in the renal system. They are located on the left and right in the retroperitoneal space and are about 11 cm in length in adult humans. The functional substance, or paren...
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Endocrine and Metabolic Diseases
The endocrine system is the collection of glands that produce hormones that regulate metabolism, growth and development, tissue function, sexual function, reproduction, sleep, and mood. In human beings, the ma...
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Liver Diseases
The liver, with four lobes of unequal size and shape, is a reddish-brown, wedge-shaped organ with dual blood supply. As the heaviest parenchymatous organ in the human body, it mainly lies in the right upper ab...
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Neurological Disease
The nervous system, containing billions of nerves and specialized cells known as neurons, is essentially the electrical wiring of the body. Structurally, the nervous system is composed of the central nervous s...
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Article
Prenatal Diagnosis for Restrictive Dermopathy Caused by Novel Mutations in ZMPSTE24 Gene and Review of Clinical Features and Pathogenic Mutations Described in Literatures
Restrictive dermopathy (RD) is a rare disorder causing stillbirth or early neonatal death. Mutations in ZMPSTE24 and LMNA genes are reported as the causes of RD. In this report, we identified two novel, biparenta...
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Article
Pathological cardiac hypertrophy: the synergy of adenylyl cyclases inhibition in cardiac and immune cells during chronic catecholamine stress
Response to stressors in our environment and daily lives is an adaptation conserved through evolution as it is beneficial in enhancing the survival and continuity of humans. Although stressors have evolved, th...
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Article
Open AccessEstrogen regulation of cardiac cAMP-L-type Ca2+ channel pathway modulates sex differences in basal contraction and responses to β2AR-mediated stress in left ventricular apical myocytes
Male and female hearts have many structural and functional differences. Here, we investigated the role of estrogen (E2) in the mechanisms of sex differences in contraction through the cAMP-L-type Ca2+channel path...
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Article
Rare Copy Number Variations Might Not be Involved in the Molecular Pathogenesis of PA–IVS in an Unselected Chinese Cohort
Congenital heart defect (CHD) is one of the most common birth defects in China, while pulmonary atresia with intact ventricular septum (PA–IVS) is the life-threatening form of CHD. Numerous previous studies re...
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Article
Clinical Application of Chromosome Microarray Analysis in Han Chinese Children with Neurodevelopmental Disorders
Chromosome microarray analysis (CMA) is a cost-effective molecular cytogenetic technique that has been used as a first-line diagnostic test in neurodevelopmental disorders in the USA since 2011. The impact of ...
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Article
TaGW2-6A allelic variation contributes to grain size possibly by regulating the expression of cytokinins and starch-related genes in wheat
Functional allelic variants of TaGW2 - 6A produce large grains, possibly via changes in endosperm cells and dry matter by...
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Article
Open AccessTunable Band-Stop Filters for Graphene Plasmons Based on Periodically Modulated Graphene
Tunable band-stop filters based on graphene with periodically modulated chemical potentials are proposed. Periodic graphene can be considered as a plasmonic crystal. Its energy band diagram is analyzed, which ...
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Article
Open AccessA modified multiplex ligation-dependent probe amplification method for the detection of 22q11.2 copy number variations in patients with congenital heart disease
Copy number variations (CNVs) of chromosomal region 22q11.2 are associated with a subset of patients with congenital heart disease (CHD). Accurate and efficient detection of CNV is important for genetic analys...
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Article
A non-convex algorithm framework based on DC programming and DCA for matrix completion
Matrix completion aims to recover an unknown low-rank or approximately low-rank matrix from a sampling set of its entries. It is shown that this problem can be solved via its tightest convex relaxation obtaine...
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Article
A majorization–minimization weighted soft thresholding algorithm for weighted nuclear norm minimization
Matrix completion problem refers to complete a low-rank matrix by observing only a few elements of the matrix. A traditional model to solve this problem is to transfer the minimization of rank into a nuclear n...
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Article
Open AccessChromosome microarray testing for patients with congenital heart defects reveals novel disease causing loci and high diagnostic yield
Congenital heart defects (CHD), as the most common congenital anomaly, have been reported to be frequently associated with pathogenic copy number variants (CNVs). Currently, patients with CHD are routinely off...
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Article
Identification of one novel and nine recurrent mutations of the ATP7B gene in 11 children with Wilson disease
Wilson disease (WND), also called hepatolenticular degeneration, is an autosomal recessive genetic disorder in which copper abnormally accumulates in several organs. WND arises from the defective ATP7B gene, whic...
