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Article
Open AccessElimination of PCR duplicates in RNA-seq and small RNA-seq using unique molecular identifiers
RNA-seq and small RNA-seq are powerful, quantitative tools to study gene regulation and function. Common high-throughput sequencing methods rely on polymerase chain reaction (PCR) to expand the starting materi...
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Article
The evolutionarily conserved piRNA-producing locus pi6 is required for male mouse fertility
Pachytene PIWI-interacting RNAs (piRNAs), which comprise >80% of small RNAs in the adult mouse testis, have been proposed to bind and regulate target RNAs like microRNAs, cleave targets like short interfering ...
