Skip to main content

3 Result(s)

within Deniz M. Özata Remove this filter

and

  1. Article

    Open Access

    Long first exons and epigenetic marks distinguish conserved pachytene piRNA clusters from other mammalian genes

    In the male germ cells of placental mammals, 26–30-nt-long PIWI-interacting RNAs (piRNAs) emerge when spermatocytes enter the pachytene phase of meiosis. In mice, pachytene piRNAs derive from ~100 discrete aut...

    Tianxiong Yu, Kaili Fan, Deniz M. Özata, Gen Zhang, Yu Fu… in Nature Communications (2021)

    Download PDF (5572 KB) View Article

  2. No Access

    Article

    The evolutionarily conserved piRNA-producing locus pi6 is required for male mouse fertility

    Pachytene PIWI-interacting RNAs (piRNAs), which comprise >80% of small RNAs in the adult mouse testis, have been proposed to bind and regulate target RNAs like microRNAs, cleave targets like short interfering ...

    Pei-Hsuan Wu, Yu Fu, Katharine Cecchini, Deniz M. Özata, Amena Arif… in Nature Genetics (2020)

  3. No Access

    Article

    Evolutionarily conserved pachytene piRNA loci are highly divergent among modern humans

    In the fetal mouse testis, PIWI-interacting RNAs (piRNAs) guide PIWI proteins to silence transposons but, after birth, most post-pubertal pachytene piRNAs map to the genome uniquely and are thought to regulate...

    Deniz M. Özata, Tianxiong Yu, Haiwei Mou, Ildar Gainetdinov… in Nature Ecology & Evolution (2020)