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Article
“Aberrant” expression of skeletal muscle markers in neuroendocrine carcinomas: a significant diagnostic pitfall
In this study, we investigate the expression of muscle markers, including the specific skeletal muscle markers myogenin and myoD1, in neuroendocrine carcinomas (NECs). The study included 23 NECs from various s...
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Article
Open AccessNon-inferiority randomised phase 3 trial comparing two radiation schedules (single vs. five fractions) in malignant spinal cord compression
The optimal EBRT schedule for MSCC is undetermined. Our aim was to determine whether a single fraction (SF) was non-inferior to five daily fractions (5Fx), for functional motor outcome.
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Chapter
Perihilar and Distal Extrahepatic Bile Duct Carcinoma
Perihilar and Distal Extrahepatic Bile Duct Carcinoma: this chapter outlines the incidence, risk factors, clinical presentation, investigations, treatments and prognosis of cancer at this anatomical site. Thes...
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Chapter
Liver Carcinoma
Liver Carcinoma: this chapter outlines the incidence, risk factors, clinical presentation, investigations, treatments and prognosis of cancer at this anatomical site. These features are correlated with the cor...
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Chapter
Ampulla of Vater and Head of Pancreas Carcinomas
Ampulla of Vater and Head of Pancreas Carcinomas: this chapter outlines the incidence, risk factors, clinical presentation, investigations, treatments and prognosis of cancer at this anatomical site. These fea...
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Chapter
Gallbladder
This chapter outlines the anatomy, clinical presentation, and relevant clinical investigations. Details of both non-neoplastic and neoplastic pathological conditions affecting the gallbladder are given. Clinic...
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Chapter
Liver
This chapter outlines the anatomy, clinical presentation, and relevant clinical investigations. Details of both non-neoplastic and neoplastic pathological conditions affecting the liver are given. This include...
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Chapter
Pancreas, Duodenum, Ampulla of Vater and Extrahepatic Bile Ducts
This chapter outlines the anatomy, clinical presentation, and relevant clinical investigations. Details of both non-neoplastic and neoplastic pathological conditions affecting the pancreas, duodenum, ampulla o...
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Article
Open AccessInversion of Spin Signal and Spin Filtering in Ferromagnet|Hexagonal Boron Nitride-Graphene van der Waals Heterostructures
Two dimensional atomically thin crystals of graphene and its insulating isomorph hexagonal boron nitride (h-BN) are promising materials for spintronic applications. While graphene is an ideal medium for long d...
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Article
Digital slide viewing for primary reporting in gastrointestinal pathology: a validation study
Despite the increasing availability of digital slide viewing, and numerous advantages associated with its application, a lack of quality validation studies is amongst the reasons for poor uptake in routine pra...
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Chapter and Conference Paper
What Can We Learn About Magnetization Dynamics from First-Principles Calculations?
A first-principles formulation of scattering theory that includes disorder, spin-orbit coupling and non-collinearity is used to study the resistance of realistic domain wall (DW) profiles, to calculate spin-fl...
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Article
Open AccessThe role of whole brain radiation therapy in the management of melanoma brain metastases
Brain metastases are common in patients with melanoma, and optimal management is not well defined. As melanoma has traditionally been thought of as “radioresistant,” the role of whole brain radiation therapy (...
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Article
Linear accelerator-based stereotactic radiosurgery for brainstem metastases: the Dana-Farber/Brigham and Women’s Cancer Center experience
To review the safety and efficacy of linear accelerator-based stereotactic radiosurgery (SRS) for brainstem metastases. We reviewed all patients with brain metastases treated with SRS at DF/BWCC from 2001 to 2...
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Article
Unexpected late radiation neurotoxicity following bevacizumab use: a case series
The purpose of this case series is to report the unexpected occurrence of four cases of late radiation-induced neurotoxicity with bevacizumab use following radiotherapy to the CNS. We retrospectively reviewed ...
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Article
Consensus for the management of patients with gastric polyps
Gastric polyps are a heterogeneous group of lesions that have differing consequences for patients, particularly in terms of malignant potential. However, there is currently no consensus for the management of p...
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Article
Genetic Factors in Osteoporosis
Osteoporosis is a common disease that affects 1 in 3 women. Family and twin studies have demonstrated that there is a strong genetic component to this condition. Potential candidate genes examined for their re...
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Article
Correction: Prediction of bone density from vitamin D raceptor alleles
Nature 367, 284-287 (1994) .... In order to expand our original observations of a relationship between bone density and vitamin D receptor (VDR) genotype and to examine other genes potentially involved in bone...
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Article
Giant Magnetoresistance and Electronic Structure
The electronic structure of magnetic multilayers is expected to play an important role in determining their transport properties. We explain how the conductance through a ballistic point contact is related to ...
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Article
Prediction of bone density from vitamin D receptor alleles
BONE density achieved in early adulthood is the major determinant of risk of osteoporotic fracture. Up to 60% of women1,2 suffer osteoporotic fractures as a result of low bone density2, which is under strong gene...
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Article
Hypercalcaemia of malignancy
Hypercalcaemia in malignancy is a major clinical problem. It contributes significantly to morbidity and mortality and can present difficult diagnostic and management dilemmas. Direct bony invasion by tumour ce...
