141 Result(s)

Article

No prokaryotic GPI anchoring (reply)

H.C Jung, J.G. Pan in Nature Biotechnology (1998)

Article

In situ delivery of passive immunity by lactobacilli producing single-chain antibodies

Lactobacilli have previously been used to deliver vaccine components for active immunization in vivo. Vectors encoding a single-chain Fv (scFv) antibody fragment, which recognizes the streptococcal antigen I/II (...

Carina Krüger, Yanzhong Hu, Qiang Pan, Harold Marcotte… in Nature Biotechnology (2002)

Article

Identification and Experimental Verification of Protective Antigens Against Streptococcus suis Serotype 2 Based on Genome Sequence Analysis

Streptococcus suis serotype 2 (S. suis 2) is an important zoonotic pathogen that can cause severe disease and even death in both humans and swine. No effective vaccine is clinically avail...

Lina Liu, Gong Cheng, Changjun Wang, **uzhen Pan, Yanguang Cong… in Current Microbiology (2009)

Article

Inactivation of Dipeptidyl Peptidase IV Attenuates the Virulence of Streptococcus suis Serotype 2 that Causes Streptococcal Toxic Shock Syndrome

Di-peptidyl peptidase IV (DPP IV), originally recognized as CD26 in eukaryotic cells, is distributed widely in microbial pathogens, including Streptococcus suis (S. suis), an emerging zoonotic agent. However, the...

Junchao Ge, Youjun Feng, Hongfeng Ji, Huimin Zhang, Feng Zheng… in Current Microbiology (2009)

Article

Chemical diversity of biologically active metabolites in the sclerotia of Inonotus obliquus and submerged culture strategies for up-regulating their production

Inonotus obliquus (Fr.) Pilat is a white rot fungus belonging to the family Hymenochaetaceae in the Basidiomycota. In nature, this fungus rarely forms a fruiting body but usually an irregular shape of sclerotial ...

Weifa Zheng, Kangjie Miao, Yubing Liu… in Applied Microbiology and Biotechnology (2010)

Article

Characterization of diverse natural variants of CYP102A1 found within a species of Bacillus megaterium

An extreme diversity of substrates and catalytic reactions of cytochrome P450 (P450) enzymes is considered to be the consequence of evolutionary adaptation driven by different metabolic or environmental demand...

Ji-Yeon Kang, So-Young Kim, Dooil Kim, Dong-Hyun Kim, Sun-Mi Shin… in AMB Express (2011)

Article

The genomic sequence of the Chinese hamster ovary (CHO)-K1 cell line

Since 1987, immortalized cells from the ovary of a Chinese hamster have been the workhorse for producing recombinant therapeutics, including monoclonal antibodies, blood factors, hormones, growth factors and e...

Xun Xu, Harish Nagarajan, Nathan E Lewis, Shengkai Pan, Zhiming Cai… in Nature Biotechnology (2011)

Article

PPARδ regulates satellite cell proliferation and skeletal muscle regeneration

Peroxisome proliferator-activated receptors (PPARs) are a class of nuclear receptors that play important roles in development and energy metabolism. Whereas PPARδ has been shown to regulate mitochondrial biosy...

Alison R Angione, Chunhui Jiang, Dongning Pan, Yong-Xu Wang… in Skeletal Muscle (2011)

Article

Microarchitecture and Nanomechanical Properties of Trabecular Bone After Strontium Administration in Osteoporotic Goats

Strontium (Sr) ralenate is a new agent used for the prevention and treatment of osteoporosis. As a bone-seeking element, 98% of Sr is deposited in the bone and teeth after oral ingestion. However, the effect o...

Zhaoyang Li, Songlin Peng, Haobo Pan, Bin Tang… in Biological Trace Element Research (2012)

Article

Erratum: Amelioration of sepsis by inhibiting sialidase-mediated disruption of the CD24-SiglecG interaction

Nat. Biotechnol. 29, 428–435 (2011); published online 6 May 2011; corrected after print 18 January 2012 In the version of this article initially published, a line in the abstract read, “repressed by the t inte...

Guo-Yun Chen, ** Chen, Samantha King, Karen A Cavassani… in Nature Biotechnology (2012)

Article

Genome sequence of foxtail millet (Setaria italica) provides insights into grass evolution and biofuel potential

Completion of genome sequences for the diploid Setaria italica reveals features of C₄ photosynthesis that could enable improvement of the polyploid biofuel crop switchgrass (Panicum virgatum). The genetic basis o...

Gengyun Zhang, **n Liu, Zhiwu Quan, Shifeng Cheng, Xun Xu… in Nature Biotechnology (2012)

Article

RETRACTED ARTICLE: Simultaneous expression of antibody light and heavy chains in Pichia pastoris: improving retransformation outcome by linearizing vector at a different site

Yueming Qian, Xuankuo Xu, Zizhuo **ng, Li You… in Applied Microbiology and Biotechnology (2012)

Article

Sequencing and automated whole-genome optical map** of the genome of a domestic goat (Capra hircus)

An instrument for whole-genome optical map** is used to assemble the genome of the domestic goat into super-long scaffolds.

Yang Dong, Min **e, Yu Jiang, Nianqing **ao, **aoyong Du… in Nature Biotechnology (2013)

Article

Evaluation and analysis of dengue virus enhancing and neutralizing activities using simple high-throughput assays

The risk of antibody-dependent enhancement (ADE) of dengue virus (DENV) infection is a major obstacle for the development of dengue vaccine candidates. Here, we described a novel approach for assessment of ADE...

**ao-Quan Li, **g Chen, Yan-Fen Huang… in Applied Microbiology and Biotechnology (2013)

Article

Mercurial-resistance determinants in Pseudomonas strain K-62 plasmid pMR68

We report the complete nucleotide sequence of plasmid pMR68, isolated from Pseudomonas strain K-62, two plasmids contribute to broad-spectrum mercury resistance and that the mer operon from one of them (pMR26) ha...

Yuka Sone, Yusuke Mochizuki, Keita Koizawa, Ryosuke Nakamura… in AMB Express (2013)

Article

Increase methylmercury accumulation in Arabidopsis thaliana expressing bacterial broad-spectrum mercury transporter MerE

The bacterial merE gene derived from the Tn21 mer operon encodes a broad-spectrum mercury transporter that governs the transport of methylmercury and mercuric ions across bacterial cytoplasmic membranes, and this...

Yuka Sone, Ryosuke Nakamura, Hidemitsu Pan-Hou, Masa H Sato, Tomoo Itoh… in AMB Express (2013)

Article

Diversity and biochemical features of culturable fungi from the coastal waters of Southern China

Fungi play a major role in various biogeochemical cycles of terrestrial and marine ecosystems. However, fungi in marine environments remain to be one of the most under-studied microbial groups. This study inve...

Li Li, Purnima Singh, Ying Liu, Shenquan Pan, Guangyi Wang in AMB Express (2014)

Article

LecT-Hepa facilitates estimating treatment outcome during interferon therapy in chronic hepatitis C patients

A combination treatment of interferon and ribavirin is the standard and the commonly used treatment for chronic hepatitis C (CHC). Develo** noninvasive tests like serum indicators that can predict treatment ...

**a Zou, **umei Chi, Yu Pan, Dongning Du, Haibo Sun, Atsushi Matsuda… in Clinical Proteomics (2014)

Article

Sequencing of allotetraploid cotton (Gossypium hirsutum L. acc. TM-1) provides a resource for fiber improvement

Two draft sequences of Gossypium hirsutum, the most widely cultivated cotton species, provide insights into genome structure, genome rearrangement, gene evolution and cotton fiber biology.

Tianzhen Zhang, Yan Hu, Wenkai Jiang, Lei Fang, Xueying Guan… in Nature Biotechnology (2015)

Article

Marine lectins and their medicinal applications

Marine organisms have been extensively explored for the last several decades as potential sources of novel biologically active compounds, and extensive research has been conducted on lectins. Lectins derived f...

Randy Chi Fai Cheung, Jack Ho Wong, Wenliang Pan… in Applied Microbiology and Biotechnology (2015)