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Article
Nimotuzumab and radiotherapy for treatment of newly diagnosed diffuse intrinsic pontine glioma (DIPG): a phase III clinical study
Diffuse intrinsic pontine glioma (DIPG) is a devastating cancer of childhood and adolescence.
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Article
High-dose chemotherapy (HDCT) with auto-SCT in children with atypical teratoid/rhabdoid tumors (AT/RT): a report from the European Rhabdoid Registry (EU-RHAB)
A retrospective analysis of data from the European Rhabdoid Registry (EU-RHAB) was performed to describe the outcome of children with atypical teratoid/rhabdoid tumors (AT/RT) who underwent high-dose chemother...
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Article
Dasatinib medication causing profound immunosuppression in a patient after haploidentical SCT: functional assays from whole blood as diagnostic clues
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Article
Long-term follow-up of children conditioned with Treosulfan: German and Austrian experience
We report the long-term follow-up of children transplanted with Treosulfan (TREO)-based conditioning in Germany and Austria. Nine centres reported a total of 109 transplantations. Patients were stratified acco...
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Article
Bearbeitung und Transplantation hämatopoetischer Stammzellen
Neue Methoden zur Anreicherung und Depletion definierter Zellpopulationen haben es möglich gemacht, hämatopoetische Stammzellen in hoher Reinheit von gesunden Spendern zu gewinnen.
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Chapter
Onkologie — KMT
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Chapter
Hirntumoren
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Article
Transplantation of highly purified peripheral-blood CD34+ progenitor cells from related and unrelated donors in children with nonmalignant diseases
Transplantation of allogeneic stem cells is currently the only curative treatment for some nonmalignant pediatric diseases. We investigated whether transplantation of purified CD34+ stem cells prevents acute and ...
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Article
A prospective comparison of immune reconstitution in pediatric recipients of positively selected CD34+ peripheral blood stem cells from unrelated donors vs recipients of unmanipulated bone marrow from related donors
Positively selected CD34+ hematopoietic stem cells from unrelated donors (UD-HSCT) have been successfully transplanted, but little is known about immune reconstitution in this setting. Here we report a prospectiv...
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Chapter and Conference Paper
Immune Reconstitution after Haploidentical Stem Cell Transplantation
With increasing efficacy and safety of the procedure in recent years, the transplantation of hematopoietic stem cells has become an important therapeutic modality for patients with a variety of malignant and n...
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Chapter
Onkologie/KMT
Noch in seinem Lehrbuch der Pädiatrie aus dem Jahre 1972 schrieb Guido Fanconi, die Prognose der Leukämie im Kindesalter sei infaust. Wenige Kinder erreichten eine Remission, und bei 1-3% von ihnen halte sie l...
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Article
Hepatic veno-occlusive disease in pediatric stem cell recipients: successful treatment with continuous infusion of prostaglandin E1 and low-dose heparin
Limited data exist on therapeutic options for established hepatic veno-occlusive disease (VOD) in pediatric patients after stem cell transplantation (SCT). In this report, we present data on the successful treat...