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  1. No Access

    Article

    Intracranial pressure and electrical activity of the brain in various forms of experimental and clinical seizures

    EEG paroxysms give rise to increased cerebral blood flow even when clinical seizure symptoms are induced to disappear completely by controlled artificial respiration. The concomitant rise of intracranial press...

    O. E. Knoblich, M. Gaab, W. Weber, K. Dietrich, R. Meyendorf in Neurosurgical Review (1980)

  2. No Access

    Chapter and Conference Paper

    ICP and EEG in Various Forms of Cerebral Seizures

    Cerebral seizures lead to an increase in cerebral blood flow (CBF). The increased blood flow is brought about by vascular dilatation created by a reduced pH due to raised CO2 and increased lactate(l). It can also...

    O. E. Knoblich, M. Gaab, W. Weber in Intracranial Pressure IV (1980)

  3. No Access

    Chapter and Conference Paper

    Beobachtung von Verlauf und therapeutischer Beeinflussung des intrakraniellen Druckes mit miniaturisierten gering invasiven Methoden

    Der intrakranielle Druck ist ein für das Überleben des Gehirnes ebenso wichtiger Parameter wie der arterielle Blutdruck und eine genügende Sauerstoff- und Glukoseversorgung [8, 5, 19]. Ein Anstieg des intrakra...

    M. Gaab, O. E. Knoblich, G. Cunitz in 25 Jahre DGAI (1980)

  4. No Access

    Chapter and Conference Paper

    Effect of Tham on ICP, EEG and Tissue Edema Parameters in Experimental and Clinical Brain Edema

    In the treatment of brain swelling, it is not only necessary to reduce the elevated intracranial pressure (ICP), which is a symptom, but also to counteract the causal pathogenetic factors, one of which is the ...

    M. Gaab, O. E. Knoblich, A. Spohr, H. Boneke, U. Fuhrmeister in Intracranial Pressure IV (1980)

  5. No Access

    Article

    Effect of furosemide (Lasix) on acute severe experimental cerebral edema

    The effect of furosemide (Lasix) therapy on a standardized experimental cerebral edema, induced in rats by applying a cooling stamp to the right side of the skull over the right coronal suture by means of a st...

    M. Gaab, O. E. Knoblich, J. Schupp, F. Herrmann, U. Fuhrmeister… in Journal of Neurology (1979)

  6. No Access

    Article

    Miniaturisierte Methoden zur Überwachung des intrakraniellen Druckes

    The prognosis of numerous diseases of the central nervous system is essentially determined by the intracranial pressure (ICP) and its therapeutic influencing. Long-term monitoring of the ICP must therefore be ...

    M. Gaab, O. E. Knoblich, K. Dietrich in Langenbecks Archiv für Chirurgie (1979)

  7. No Access

    Chapter and Conference Paper

    Prognostic Information From EEG and ICP Monitoring After Severe Closed Head Injuries in the Early Post-Traumatic Phase

    In conventional EEG recordings, an amplitude flattening and slowing of frequency is found in the first hours after severe enclosed head injuries, without correlation with clouding of consciousness and prognosi...

    O. E. Knoblich, M. Gaab in Proceedings of the 6th European Congress of Neurosurgery (1979)

  8. No Access

    Article

    Wirkung unterschiedlicher Osmo- und Onkotherapie auf Hirndruck und elektrische Hirnaktivität beim experimentellen Hirnödem

    Die beim Hirnödem gebräuchlichen Osmo- und Onkotherapeutika (Mannit, Sorbit, Glycerin; Albumin, Dextran) verhalten sich pharmakologisch unterschiedlich. Es sind daher unterschiedliche Wirkungen auf den erhöhte...

    M. Gaab, O. E. Knoblich, J. Schupp, K. Dietrich, U. Fuhrmeister… in Acta Neurochirurgica (1978)

  9. No Access

    Chapter and Conference Paper

    Comparison of the Effects of Osmotherapeutic Agents, Hyperventilation, and Tromethamine (THAM) on Brain Pressure and Electric Activity of the Brain in Experimental and Clinical Brain Edema

    In the presence of brain edema, intracranial pressure (ICP) is raised by the space-occupying swelling of the brain (14), whereas cerebral perfusion pressure is reduced and the pH of the brain tissue falls (3). Th...

    O. E. Knoblich, M. Gaab, U. Fuhrmeister… in Head Injuries. Tumors of the Cerebellar Re… (1978)

  10. No Access

    Chapter and Conference Paper

    Disorders of CSF Circulation After Interventions in the Area of the Posterior Cranial Fossa With Prior Shunt Operation

    Compressing processes in the posterior cranial fossa very often cause hydrocephalus (3). This frequently appears earlier than the “local signs,” e.q., cerebellar ataxia, disorders of the eye, or cranial nerves. S...

    P. Gruss, M. Gaab, O. E. Knoblich in Head Injuries. Tumors of the Cerebellar Region (1978)

  11. No Access

    Chapter and Conference Paper

    Miniaturized Methods of Monitoring Intracranial Pressure in Craniocerebral Trauma Before and After Operation

    One of the essential problems in brain injuries is the early recognition, diagnostic clarification, and precise treatment of post-traumatic increases in intracranial pressure (1, 4, 7). A continuous monitoring of...

    M. Gaab, O. E. Knoblich, K. Dietrich… in Head Injuries. Tumors of the Cerebellar Re… (1978)

  12. No Access

    Chapter and Conference Paper

    Therapy of Experimental Brain Edema in Cats

    Up to now, continuous experimental monitoring of the acidotic tissue metabolism (2, 10) in brain edema has been impossible. If biochemical tissue analysis is used, the effectiveness of various forms of treatme...

    M. Gaab, O. E. Knoblich, K. Dietrich, J. Schupp… in Lumbar Disc Adult Hydrocephalus (1977)