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  1. Article

    Locomotor improvement of spinal cord-injured rats through treadmill training by forced plantar placement of hind paws

    Experimental training model of rats with spinal cord injury (SCI).

    M Hayashibe, T Homma, K Fujimoto, T Oi, N Yagi, M Kashihara, N Nishikawa in Spinal Cord (2016)

  2. Article

    Open Access

    Plasma microRNA profiles: identification of miR-25 as a novel diagnostic and monitoring biomarker in oesophageal squamous cell carcinoma

    Recent studies have demonstrated that microRNAs are stably detectable in plasma/serum because of their binding to specific proteins or being packaged in secretory particles. This study was designed to detect n...

    S Komatsu, D Ichikawa, S Hirajima, T Kawaguchi, M Miyamae in British Journal of Cancer (2014)

  3. Article

    The Effect of Changing Positive End-Expiratory Pressures on the Spatial Pattern of Lung Ventilation in Newborn Rabbits Ventilated from Birth

    Background: Positive end-expiratory pressure (PEEP) helps very preterm newborns develop functional residual capacity (FRC) and establish adequate gas exchange at birth. In the immediate newborn period, lungs comm...

    M L Siew, M J Kitchen, A B te Pas, M J Wallace, M S Islam, N Yagi in Pediatric Research (2011)

  4. No Access

    Chapter and Conference Paper

    Optimising Coherence Properties for Phase Contrast X-Ray Imaging (PCXI) to Reveal Airway Surface Liquid (ASL) as an Airway Health Measure

    We demonstrate the potential of PCXI in achieving a non-invasive measure of airway health, for the assessment of new therapies for cystic fibrosis (CF). In particular, the advantages to an increased transverse...

    K. S. Morgan, D. M. Paganin, D. W. Parsons in World Congress on Medical Physics and Biom… (2009)

  5. No Access

    Chapter and Conference Paper

    Increasing Preload Reduced Actin-Myosin Interaction in Isolated Beating Rat Whole Heart Under Hypoxia

    Background: Hypoxia reduces cardiac contractile performance. However, there is no direct observation on how preload affects the actinmyosin-interaction (AMI) in beating hearts during hypoxia. Purpose: The aim ...

    J. Shimizu, T. Miyasaka, Y. Tamura in World Congress on Medical Physics and Biom… (2009)

  6. No Access

    Article

    A vertebrobasilar junction aneurysm associated with fenestration treated by intra-aneurysmal embolization

    Y. Ezaki, K. Kazekawa, K. Tsutsumi, N. Yagi, K. Mori, J. Kawakubo in Acta Neurochirurgica (2003)

  7. No Access

    Article

    Effects of inorganic phosphate on cross-bridge behavior after photorelease of ATP in permeabilized cells of rat skeletal muscle

    Effects of 20 mM inorganic phosphate on the cross-bridge behavior after photorelease of ATP from caged ATP was studied by X-ray diffraction in rat skinned psoas muscle fibers at 16°C. In the first 30 ms after...

    N. Yagi, K. Horiuti, S. Takemori in Pflügers Archiv (2002)

  8. No Access

    Article

    Single turnover of cross-bridge ATPase in rat muscle fibers studied by photolysis of caged ATP

    A mechanical study on skinned rat psoas muscle fibers was performed at about 16°C with X-ray diffraction and caged-ATP photolysis. The amount of photoreleased ATP was set <0.2 mM for analysis of a `single turn...

    K. Horiuti, N. Yagi, S. Takemori in Journal of Muscle Research & Cell Motility (2001)

  9. No Access

    Article

    Structural changes in myosin cross-bridges during shortening of frog skeletal muscle

    X-ray diffraction patterns from frog sartorius muscle were recorded during steady shortening with various loads. The intensity of the third meridional reflection from the thick filament decreased on shortening...

    N. Yagi, S. Takemori in Journal of Muscle Research & Cell Motility (1995)

  10. No Access

    Article

    X-ray diffraction study on mammalian visceral smooth muscles in resting and activated states

    Structural changes of guinea pig taenia coli and rat anococcygeus muscle during contraction were studied by X-ray diffraction. The diffraction pattern of the taenia coli showed the 14.4-nm myosin reflection, t...

    M. Watanabe, S. Takemori, N. Yagi in Journal of Muscle Research & Cell Motility (1993)

  11. No Access

    Chapter

    Current X-Ray Diffraction Experiments using a Synchrotron Radiation Source

    A Fuji imaging plate and synchrotron radiation are the most distinct innovations of the last twenty years in the X-ray diffraction experiments on biological materials. Here we present results of recent experim...

    N. Yagi, S. Takemori, M. Watanabe in Mechanism of Myofilament Sliding in Muscle Contraction (1993)

  12. No Access

    Article

    Effects of N-ethylmaleimide on the structure of skinned frog skeletal muscles

    The effects of N-ethylmaleimide (NEM) and other sulfhydryl modifiers on the structure of skinned frog skeletal muscles were studied using the X-ray diffraction technique. In sartorius muscle with full overlap ...

    N. Yagi in Journal of Muscle Research & Cell Motility (1992)

  13. No Access

    Article

    Effects of 2,3-butanedione monoxime on contraction of frog skeletal muscles: An X-ray diffraction study

    We studied the effects of BDM (2,3-butanedione monoxime) on the tetanic contraction of frog skeletal muscles using an X-ray diffraction technique. BDM significantly increased the resting equatorial intensity r...

    N. Yagi, S. Takemori, M. Watanabe, K. Horiuti in Journal of Muscle Research & Cell Motility (1992)

  14. No Access

    Article

    An X-ray diffraction study ofα-tropomyosin magnesium tactoid

    The structure of the needle-shaped aggregate ofα-tropomyosin formed in the presence of Mg2+ ions (the Mg-tactoid) was studied by X-ray diffraction. Orientated specimens were prepared by magnetic orientation. The ...

    N. Yagi in Journal of Muscle Research & Cell Motility (1988)

  15. No Access

    Article

    Intensification of the 5.9-nm actin layer line in contracting muscle

    According to the cross-bridge model1–3 of muscle contraction, an interaction of myosin heads with interdigitating actin filaments produces tension. Although X-ray equatorial diffraction patterns of active (contra...

    I. Matsubara, N. Yagi, H. Miura, M. Ozeki, T. Izumi in Nature (1984)

  16. No Access

    Chapter

    Lateral Shrinkage of the Myofilament Lattice in Chemically Skinned Muscles during Contraction

    A toe muscle was isolated from a hind limb of the mouse and treated with saponin to make the sarcolemma more permeable to the solutes of the bathing medium. The equatorial X-ray diffraction pattern was recorde...

    I. Matsubara, Y. Umazume, N. Yagi in Contractile Mechanisms in Muscle (1984)

  17. No Access

    Article

    Effects of glycerol on sodium and potassium concentrations in guinea pig perilymph

    Blutserum, Liquor cerebrospinalis und Perilymphe von Scala vestibuli und Scala tympani wurden von 85 normalen Meerschweinchen vor und nach i.v. Glycerolapplikation entnommen und die Na- und K-Konzentration bes...

    N. Kanoh, N. Yagi, M. Omura, K. Makimoto in Archives of oto-rhino-laryngology (1981)

  18. No Access

    Article

    Movement of myosin heads during a heart beat

    X-RAY diffraction studies of heart muscle undergoing cyclic contractions have shown that the myosin heads are transferred from the vicinity of the thick filaments to that of the thin filaments as the muscle pa...

    I. MATSUBARA, N. YAGI, M. ENDOH in Nature (1979)

  19. Article

    Behaviour of myosin projections during the staircase phenomenon of heart muscle

    PEAK tension of an excised heart muscle increases with the frequency of contraction1. This ‘staircase’ phenomenon has been attributed to changes in the distribution of Ca ions; it has been proposed that the sarco...

    I. MATSUBARA, N. YAGI, M. ENDOH in Nature (1978)

  20. No Access

    Article

    Equatorial X-ray reflections from contracting muscle after an applied stretch

    The equatorial X-ray reflections were recorded from contracting muscle after a slow stretch. The intensity ratio of the 1,0 to the 1,1 reflections (I10/I11) after the stretch was not significantly different from ...

    N. Yagi, I. Matsubara in Pflügers Archiv (1977)

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