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Article
Open AccessOverexpression of SMYD2 contributes to malignant outcome in gastric cancer
SET and MYND domain-containing protein 2 (SMYD2) is a lysine methyltransferase for histone H3, p53 and Rb and inhibits their transactivation activities. In this study, we tested whether SMYD2 (1q42) acts as a can...
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Article
Open AccessPlasma microRNA profiles: identification of miR-25 as a novel diagnostic and monitoring biomarker in oesophageal squamous cell carcinoma
Recent studies have demonstrated that microRNAs are stably detectable in plasma/serum because of their binding to specific proteins or being packaged in secretory particles. This study was designed to detect n...
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Article
Open AccessClinical impact of circulating miR-18a in plasma of patients with oesophageal squamous cell carcinoma
Several recent studies demonstrated that microRNAs are stably detectable in plasma/serum. We tested whether miR-18a, which is located in the miR-17-92 cluster and reported to be highly expressed in tissues of ...
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Article
Open AccessOverexpression of YWHAZ relates to tumor cell proliferation and malignant outcome of gastric carcinoma
Several studies have demonstrated that YWHAZ (14-3-3ζ), included in the 14-3-3 family of proteins, has been implicated in the initiation and progression of cancers. We tested whether YWHAZ acted as a cancer-promo...
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Article
Open AccessClinical impact of circulating miR-221 in plasma of patients with pancreatic cancer
Several recent studies have demonstrated that microRNAs (miRNAs) are stably detectable in plasma/serum. We tested miR-221 and miR-375, which are frequently reported to be highly and poorly expressed in pancrea...
