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Article
The prognostic impact of serum testosterone during androgen-deprivation therapy in patients with metastatic prostate cancer and the SRD5A2 polymorphism
Although testosterone suppression during androgen-deprivation therapy (ADT) and obesity have been reported to affect ADT efficacy, there are few comprehensive analyses on the impact on ADT outcome. Recently, w...
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Article
Polymorphisms of the androgen transporting gene SLCO2B1 may influence the castration resistance of prostate cancer and the racial differences in response to androgen deprivation
Organic anion-transporting polypeptides (OATPs) encoded by SLCO mediate the cellular uptake of many compounds, including androgens. SLCO1B3 and SLCO2B1 are polymorphic, and single-nucleotide polymorphisms of thos...
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Chapter and Conference Paper
Basic investigation of boron neutron capture therapy (BNCT) using novel boron agents and accelerator based neutron source
Recently the number of cancer case has been increasing. In addition, because of aging of the population and diversification of values among the people, less-invasive and high-QOL (quality of life) treatment fo...
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Article
Checkpoint and physiological apoptosis in germ cells proceeds normally in spaceflown Caenorhabditis elegans
It is important for human life in space to study the effects of environmental factors during spaceflight on a number of physiological phenomena. Apoptosis plays important roles in development and tissue homeos...
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Article
Use of blue-on-yellow perimetry for detection of sectoranopia
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Article
Unique evolution of Bivalvia arginine kinases
The clams Pseudocardium, Solen, Corbicula and Ensis possess a unique form of arginine kinase (AK) with a molecular mass of 80 kDa and an unusual two-domain structure, a result of gene duplication and subsequent f...
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Article
Optic disc metastasis presenting as an initial sign of recurrence of adenoid cystic carcinoma of the larynx
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Article
Criteria for early detection of temporal hemianopia in asymptomatic pituitary tumor
Purpose To determine new criteria for early detection of temporal hemianopia in patients with asymptomatic pituitary tumor.
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Article
Heavily T2 Weighted MR Images of Anterior Optic Pathways in Patients with Sellar and Parasellar Tumours – Prediction of Surgical Anatomy
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Article
Characterization of the Neurospora crassa mus-25 mutant: the gene encodes a protein which is homologous to the Saccharomyces cerevisiae Rad54 protein
Characterization of the Neurospora crassa mus-25 mutant suggests that it is defective in recombination repair and belongs to the uvs-6 epistasis group. It shows a high sensitivity to the alkylating agents methyl...
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Article
Expression of microfibril-associated glycoprotein-1 (MAGP-1) in human epidermal keratinocytes
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Article
Measurement and evaluation of serum anti-p53 antibody levels in patients with lung cancer at its initial presentation: a prospective study
Anti-p53 antibodies in sera are known to be products of the host immune response to mutated p53 protein, and are present in some patients with various types of cancer. In this study, we measured serum anti-p53...
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Article
Imbalance between serum matrix metalloproteinase-2 and its inhibitor as a predictor of recurrence of urothelial cancer
Serum levels of matrix metalloproteinase-2 (MMP-2) and tissue inhibitor of metalloproteinases-2 (TIMP-2) were evaluated as prognostic indicators of the recurrence of urothelial cancer. Sera were obtained from ...
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Chapter and Conference Paper
The Androgen Receptor Co-regulator, ARA70
Androgens play an important role in the process of male sexual differentiation and development. Their actions are mediated by the androgen receptor (AR), which is a member of a large family of ligand-dependent...
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Chapter and Conference Paper
Estrogen-Receptor and Antiestrogen-Receptor Complexes: Cell- and Promoter-Specific Effects and Interactions with Second Messenger Signaling Pathways
Estrogens regulate the differentiation, growth, and functioning of many reproductive tissues. They also exert important actions on other tissues, including bone, liver, and the cardiovascular system. Most of t...
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Chapter
GIS Utility Research — A Historical Perspective
Gas-insulated substations (GIS) have been in use for many years worldwide, especially at the lower voltage classes. In more recent years, the promise of high reliability, low maintenance and compact size has l...
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Article
Sigmoidoscopy and other tests for screening of colorectal cancer
We have been carrying our mass detection for colorectal cancer with fecal occult blood test and sigmoidoscopy. The occult blood test is negative in 60% with colorectal cancer.
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Article
MRI of syphilitic myelitis
MR imaging was performed on a patient with syphilitic myelitis. T2-weighted images showed high intensity areas in the thoracic spinal cord. On T1-weighted images after gadolinium-DTPA injection, heterogeneous ...
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Chapter and Conference Paper
Early diagnosis of kidney transplant rejection and cyclosporin nephrotoxicity by urine cytology
A total of 2000 urine samples from 53 kidney transplant recipients were studied to develop a routine method for the early diagnosis of rejection and cyclosporin (CSA) nephrotoxicity in urine. New-Sternheimer s...
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Article
Magnetic resonance imaging of the brain in congenital rubella virus and cytomegalovirus infections
Two children with congenital rubella virus and six with cytomegalovirus (CMV) infections, were examined by magnetic resonance (MR) and CT. Cranial MR imaging (MRI) with T2-weighted spin-echo (SE) and inversion...
